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5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Women with acromegaly often have irregular periods due to hormone imbalances and growth hormone effects.

Testosterone causes hair loss in AGA mice, which are good for testing baldness treatments, and both minoxidil and cyproterone acetate can prevent this hair loss.

Testosterone affects blood pressure control and inflammation in male rats with endotoxic shock, and blocking certain hormones may help treat it.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Women with PCOS have similar levels of certain proteins compared to women without PCOS, and these proteins don't independently cause PCOS.

Prostate-specific antigen may be a new marker for excess male hormones in women with polycystic ovary syndrome.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.

The document concludes that managing PCOS involves treating symptoms and reducing long-term metabolic risks, with lifestyle changes being important.

Menopause can cause hair thinning and texture changes due to hormonal and metabolic shifts.

Metformin improved menstrual cycle regularity and signs of hyperandrogenism in adolescent girls with type 1 diabetes but did not improve blood sugar control.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

Long-term finasteride use doesn't change bone density or metabolism.

More research is needed before using brown fat to treat polycystic ovary syndrome.

Normal levels of DHT can reduce belly fat and increase muscle, but too much can lead to hair loss, prostate issues, and possibly heart disease.

Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Simvastatin may help manage symptoms in women with non-classic congenital adrenal hyperplasia by lowering cholesterol and certain hormone levels.

Finasteride, when taken daily, lowers dihydrotestosterone levels but doesn't noticeably affect adrenal steroid production, except by blocking the 5 alpha-reductase enzyme.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

Women with acne and irregular periods had higher active testosterone levels, which could suggest the usefulness of antiandrogen treatment.

Diet changes can help reduce acne by limiting certain hormones.

The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.

The testes produce important hormones like testosterone and others that play key roles in male body functions.

There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.