1 citations,
August 2021 in “Canadian journal of neurological sciences” Woodhouse-Sakati syndrome can cause writer's cramp and other varied symptoms, highlighting the importance of genetic testing for diagnosis.
156 citations,
October 1996 in “Science of The Total Environment” Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.
78 citations,
November 2008 in “Fertility and Sterility” Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.
38 citations,
October 2006 in “Fertility and Sterility” The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.
30 citations,
July 2004 in “Fertility and Sterility” Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.
21 citations,
September 2004 in “Fertility and Sterility” Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.
September 2023 in “Fides et Ratio” The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.
125 citations,
January 1999 in “Drugs” Finasteride effectively treats baldness but may cause sexual side effects.
7 citations,
January 2016 in “Experimental and Clinical Endocrinology & Diabetes” Simvastatin may help manage symptoms in women with non-classic congenital adrenal hyperplasia by lowering cholesterol and certain hormone levels.
1 citations,
September 2021 in “Frontiers in genetics” A genetic mutation in the DCAF17 gene caused Woodhouse-Sakati syndrome in a Chinese patient from a related family.
39 citations,
November 2021 in “Clinical Endocrinology” Testosterone replacement is recommended for men with low testosterone levels and symptoms of hypogonadism.
November 2013 in “John Wiley & Sons, Ltd eBooks” The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.
4 citations,
August 2021 in “Pediatrics in review” DSDs are birth conditions causing unusual sex development, managed with personalized care and sometimes surgery, but still lack a standard treatment approach.
39 citations,
January 2019 in “The World Journal of Men's Health” Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.
21 citations,
April 1995 in “Mayo Clinic Proceedings” Leydig cells can cause testosterone-secreting adrenal tumors in women.
April 2019 in “Journal of the Endocrine Society” A woman's severe male-like symptoms were caused by a rare, benign tumor in her ovary that produced male hormones.
22 citations,
January 2019 in “Endocrinology and metabolism” An mFG score of 7 or higher indicates hirsutism in Filipino women, often linked to higher free testosterone levels.
2 citations,
August 2020 in “JCRPE” A girl with Denys-Drash syndrome was misdiagnosed due to biotin affecting her hormone test results.
November 2022 in “Journal of the Endocrine Society” A boy with a new NR5A1 gene mutation has a sex development disorder without affecting his adrenal glands.
231 citations,
July 2008 in “Nutrition reviews” Diet changes can protect against harmful environmental effects on fetal development.
56 citations,
June 2001 in “European journal of cardiovascular prevention & rehabilitation” Early balding linked to higher heart disease risk.
49 citations,
December 1997 in “Urology” Tamoxifen effectively treats gynecomastia without causing impotence.
46 citations,
October 1999 in “Journal of The American Academy of Dermatology” Finasteride effectively treats male pattern hair loss with a 1 mg daily dose.
44 citations,
April 2008 in “The Journal of Clinical Endocrinology & Metabolism” Women with PCOS have similar levels of certain proteins compared to women without PCOS, and these proteins don't independently cause PCOS.
38 citations,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Finasteride effectively improves hair growth and slows hair loss in men with male pattern baldness.
34 citations,
March 2003 in “Veterinary Dermatology” Most dogs with alopecia had higher than normal levels of certain hormones, but hair loss might not always be linked to these hormone changes.
22 citations,
June 2007 in “Radiologia Medica” Testicular microlithiasis may increase the risk of testicular cancer and patients with it should be closely monitored.
21 citations,
November 2015 in “Archives of Gynecology and Obstetrics” Greek women with PCOS have a higher risk of metabolic syndrome and are more likely to be overweight compared to healthy controls.
21 citations,
December 2012 in “Maturitas” Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.