research Androgens in Women: Role in Androgen-Mediated Cutaneous Disorders
Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.
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research Matriptase Activation and Shedding with HAI-1 Induced by Steroid Sex Hormones in Human Prostate Cancer Cells, but Not in Breast Cancer Cells
Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.
research Superficial Fungal Infections
Accurate diagnosis and treatment are crucial for managing superficial fungal infections, with terbinafine being the best oral treatment for nail infections.
research Differential Expression of miR-93 and miR-21 in Granulosa Cells and Follicular Fluid of Polycystic Ovary Syndrome Associating with Different Phenotypes
The study found that certain microRNAs are higher in the cells and lower in the fluid of women with a specific type of polycystic ovary syndrome, and one microRNA could potentially help diagnose the condition.
research How to Diagnose a Lipodystrophy Syndrome
The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.
research MicroRNA Species in Follicular Fluid Associating With Polycystic Ovary Syndrome and Related Intermediary Phenotypes
Certain microRNAs in the fluid around eggs are linked to Polycystic Ovary Syndrome and may help diagnose it.
research An Approach to the Patient with Hirsutism
The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.
research Expression and Roles of Steroidogenic Acute Regulatory (StAR) Protein in Non-Classical, Extra-Adrenal, and Extra-Gonadal Cells and Tissues
The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.
research Conditional Activin Receptor Type 1B (Acvr1b) Knockout Mice Reveal Hair Loss Abnormality
Disrupting Acvr1b in mice causes severe hair loss and thicker skin.
research Primary Cicatricial Alopecia: Recent Advances in Understanding and Management
New understanding of the causes of primary cicatricial alopecia has led to better diagnosis and potential new treatments.
research Mitoxantrone
Mitoxantrone is effective for treating acute leukemia, especially in older patients, with a lower risk of heart damage.
research Hair Growth Induction: Roles of Growth Factors
EGF and FGF help hair growth by affecting cell differentiation and fiber growth.
research The CLE40 and CRN/CLV2 Signaling Pathways Antagonistically Control Root Meristem Growth in Arabidopsis
CLE40 and CRN/CLV2 pathways have opposite effects on root growth in Arabidopsis.
research Toward a Diagnostic Score in Cushing's Syndrome
The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.
research Woolly Hair Nevus: A Rare Case with Late Onset in Adolescence
A 17-year-old developed woolly hair nevus in adolescence, which is unusual, and over time the hair darkened and straightened slightly, but microscopic changes persisted.
research Network-Based Drug Repositioning: Approaches, Resources, and Research Directions
The document concludes that computational methods using networks and various data can improve the process of finding new uses for existing drugs.
research Non-Polycystic Ovary Syndrome–Related Endocrine Disorders Associated with Hirsutism
Hirsutism can be caused by various conditions besides PCOS, and it's important to treat the underlying issue and manage symptoms with medication and cosmetic approaches.
research Studying the Genetic Predisposing Factors in the Pathogenesis of Acne Vulgaris
Genetics play a role in acne, but how exactly they contribute is not fully understood.
research Side Effects of Common Acne Treatments
Common acne treatments can cause various side effects, like skin irritation and more serious issues, but combination therapies are often more effective and better tolerated.
research Topical ALA-Photodynamic Therapy for Acne Can Induce Apoptosis of Sebocytes and Down-Regulate Their TLR-2 and TLR-4 Expression
ALA-photodynamic therapy helps reduce acne by causing acne cell death and lowering certain skin protein levels.
research Adult Epidermal Notch Activity Induces Dermal Accumulation of T Cells and Neural Crest Derivatives Through Upregulation of Jagged 1
Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.
research The Influence of Interferon on Healthy and Diseased Skin
Type I interferons play a key role in the development of various skin diseases.
research The Role of Pannexin 3 in Bone Biology
Pannexin 3 is important for bone formation and the development of bone cells.
research A Clinical Approach to Severe Insulin Resistance
Severe insulin resistance can be managed with medication, lifestyle changes, and treatment for related conditions.
research Use of Insulin-Sensitizing Agents in Patients With Polycystic Ovary Syndrome
Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.
research Acne in Women
Acne is common in women, often hormone-related, negatively affects quality of life, and requires various treatments.
research What Does Acne Genetics Teach Us About Disease Pathogenesis?
Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.
research Lupus Panniculitis Clinically Simulating Alopecia Areata
Lupus can look like hair loss from alopecia areata but needs different treatment.
research An Endophytic Microbe From An Unusual Volcanic Swamp Corn Seeks And Inhabits Root Hair Cells To Extract Rock Phosphate
A special microbe helps plants absorb rock phosphate by growing on their root hairs.
research Skin Manifestations Associated with Autoimmune Liver Diseases: A Systematic Review
Autoimmune liver diseases are likely linked to certain skin conditions like vitiligo and psoriasis.