January 2023 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” This study found that the novel culture condition gHFEM, which includes Y-27632 and bFGF, optimally promotes the proliferation and pluripotency of goat hair follicle stem cells in vitro.
May 2022 in “Indian Journal of Animal Research” This study found that melatonin receptor genes play a key regulatory role in the development of goose skin feather follicles during embryonic development.
January 2017 in “Springer eBooks” Understanding genes and hormones is crucial for managing male puberty and sex development disorders.
This study investigated whether combinations of green tea leaf and gotukola extracts could act as a hair growth stimulant but reports no definitive results on the most effective combination.
January 2015 in “Proceedings of the Oklahoma Academy of Science” In this study, researchers observed that including raw cotton seeds in the diet of rats led to hair loss, suggesting gossypol in the seeds may be responsible.
November 2013 in “John Wiley & Sons, Ltd eBooks” The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.
January 2013 in “Journal of Endocrinology and Diabetes Mellitus” This study found that men with Cushing syndrome often experience significant hypogonadism, with 65% reporting reduced libido and erectile dysfunction, indicating a need for screening in those with gynecomastia or hypogonadism.
January 2003 in “Research Portal (King's College London)” This study employed a laser-based method to analyze how light reflection patterns vary on human hair fibers, revealing changes related to hair color and the tilt of the cuticle cells.
May 2017 in “Endocrine Abstracts” This study found that men with early-onset androgenetic alopecia who also met criteria for the male PCOS-equivalent may have impaired gonadal steroidogenesis, suggesting increased risk of future gonadal dysfunction.
77 citations
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March 2021 in “Nature” In this study, increased corticosterone from chronic stress prolonged hair follicle stem cell quiescence in mice, inhibiting regeneration, but restoring Gas6 expression overcame this inhibition.
77 citations
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July 2020 in “Cell” This study found that sympathetic nerves and arrector pili muscles form a niche that modulates hair follicle stem cell activity, revealing their role in hair follicle regeneration.
75 citations
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October 2016 in “Genes & Development” This study found that Sonic Hedgehog secreted by hair follicle transit-amplifying cells is essential for dermal adipogenesis and hair follicle growth by acting on adipocyte precursors.
74 citations
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January 2006 in “Endocrine journal” Low-dose gonadotropin treatment is effective for infertility in women with PCOS, leading to high ovulation rates and comparable pregnancy rates with fewer complications.
69 citations
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February 1983 in “Gut” This study found that untreated men with coeliac disease exhibited androgen resistance, potentially linked to sexual dysfunction, which improved as intestinal health improved, a pattern not observed in other chronic illnesses.
59 citations
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April 2016 in “Cell Reports” This study demonstrated that EdnrB signaling promotes melanocyte stem cell proliferation and differentiation, enhancing hair and epidermal melanocyte regeneration, especially under conditions of active Wnt signaling.
52 citations
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April 2013 in “Developmental Cell” This study found that Brg1, a chromatin-remodeling enzyme, plays a critical role in hair regeneration and early epidermal repair by regulating bulge stem cells through a Brg1-Shh interaction.
35 citations
,
March 2010 in “BMC veterinary research” The study found that while a clinical protocol showed high specificity in detecting scrapie in goats, its low sensitivity suggests many cases might be missed if diagnosis is only based on clinical signs.
34 citations
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January 2023 in “Therapeutic Advances in Medical Oncology” This study found that the safety and effectiveness of sacituzumab govitecan in patients with metastatic triple-negative breast cancer in Germany align with existing clinical trial data.
34 citations
,
December 2015 in “Neuroscience & Biobehavioral Reviews” In this study, several compounds, including estrogen and Dutasteride, showed neuroprotective effects on dopaminergic neurons in an MPTP mouse model of Parkinson's disease.
31 citations
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January 2014 in “International Journal of Trichology” This review summarizes the anatomy and physiology of the arrector pili muscle and discusses its potential role in hair loss disorders, reporting no new clinical results.
30 citations
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June 2022 in “Animals” This study found that certain genes were significantly associated with hair length in Inner Mongolia cashmere goats, potentially serving as molecular markers for different hair types.
30 citations
,
August 1992 in “The Journal of Clinical Endocrinology and Metabolism” This study found that lowering serum DHT levels with 5 mg finasteride daily did not significantly alter serum gonadotropin levels in healthy young men after 28 days.
27 citations
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April 2020 in “Molecular Biology and Evolution” This study found that ancient and modern Chinese goats share close genetic ties, originating from the Fertile Crescent, with genetic divergence influenced by China's climatic divisions.
25 citations
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June 2021 in “Developmental Cell” In this study, researchers found that deleting Caspase-9 in hair follicle stem cells delayed apoptosis, leading to accelerated wound repair and new hair follicle regeneration by maintaining apoptotic cells as signaling centers.
25 citations
,
May 2017 in “Developmental Biology” This review highlights how intravital microscopy has advanced understanding of tissue homeostasis and cancer progression, focusing on how tumor cells exploit physiological processes for growth; it reports no new experimental findings.
22 citations
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September 2022 in “Journal of Animal Science” This study suggests that the PI3K-AKT signaling pathway may significantly influence the development of different hair types in Inner Mongolia cashmere goats.
18 citations
,
November 2016 in “Transgenic research” This study found that transgenic cashmere goats overexpressing thymosin beta-4 have a higher secondary to primary hair follicle ratio, suggesting potential for increased cashmere yield.
15 citations
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July 2000 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that fluorescence excitation spectroscopy could be a promising noninvasive tool for assessing the effects of comedolytic agents like retinoids on acne-like lesions in rhino mice.
14 citations
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May 2020 in “Archiv für Tierzucht” This study found that genes such as FGF5, FGFR1, and RRAS may impact the growth cycle of secondary hair follicles in Inner Mongolian Cashmere goats.
13 citations
,
January 2014 in “Journal of Veterinary Internal Medicine” This case study reports an instance of adult-onset primary hypothyroidism with goiter in a cat, suggesting potential causes such as dietary iodine imbalance, chronic exposure to thyrotoxic substances, or a congenital form with late manifestation.