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Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.

ADAM17 could be a potential target for treating PCOS.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.

Treatment of acromegaly can improve women's reproductive health issues caused by hormonal imbalances or tumors.

Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.

Hormonal treatment in transgender women reduces semen quality, but stopping treatment may improve it.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.

Women with PCOS often have mood disorders and a lower quality of life, and treatment should focus on both physical and mental health.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Metformin improves menstrual cycles and hormone levels in women with PCOS, mostly within the first 6 months.

Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.