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Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

CDP is crucial for lung and hair follicle cell development.

Myrtle has various health benefits and potential for medicine development.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Stem cell self-renewal is complex and needs more research for full understanding.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

K6hf is a unique protein found only in a specific layer of hair follicles.

Understanding hair follicle anatomy helps diagnose hair disorders.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.

Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

Skin fat helps with body temperature control and has other active roles in health.

Wnt signaling helps control how brain stem cells divide and is important for brain repair after injury.