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The document discusses challenges in eye care, including treating melanoma before macular hole repair, bloody tears resolved by blood pressure control, eyelash regrowth in hair-pulling disorder with medication, a non-invasive method to detect eyelash mites, and the psychological factors affecting contact lens comfort.

PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.

PAD is common but often missed, needing lifestyle changes and medication for better outcomes.

Early recognition and treatment of Peripheral Arterial Disease is crucial to improve survival and health outcomes.

Using anabolic-androgenic steroids can harm men's reproductive health and increase the risk of heart problems and death.

Eating too much selenium can cause bad breath, hair loss, and nail changes, with harmful effects starting at low daily doses.

Higher BMI and lower testosterone are linked to more aggressive prostate cancer.

Girls with PCOS have higher levels of certain androgens, which are linked to excess hair growth, but these androgens don't help diagnose PCOS.

The over-the-counter supplement DHEA could make COVID-19 worse, especially in diabetics and people with G6PD deficiency.

Personalized diets, like the Mediterranean Diet and low carb diets, can help manage PCOS symptoms in obese women, and probiotics may enhance weight loss and improve metabolic health. More research is needed to find the best diet strategies.

A new mutation in the DCAF17 gene was found to cause Woodhouse-Sakati syndrome in a large family.

The review found that current care models for PCOS are not fully effective and more research is needed, especially in low-income countries.

Testosterone therapy for postmenopausal women appears safe and may protect against heart disease, but requires constant monitoring and more research for long-term effects.

Some women with PCOS have rare genetic variants linked to the condition.

A diabetic cat with another gland issue got better after treatment with cabergoline, no longer needing insulin.

Lower hair copper and copper-to-zinc ratio are linked to more severe coronary artery disease.

A postmenopausal woman's excess male hormone symptoms improved after her ovaries were removed.

Tirzepatide might help manage PCOS in obese patients but needs more research to confirm safety and effectiveness.

A 36-year-old woman with low potassium levels was found to have Cushing disease, and after treatment, her potassium levels normalized.

Men and women respond differently to drugs for COVID-19, high cholesterol, and diabetes, which suggests a need for personalized treatments.

Insulin resistance increases the risk of developing type 2 diabetes and other health issues.

Hair glycation could be a reliable non-invasive indicator of blood glucose control, but its use is limited by factors like sample collection and hair treatments.

Hibiscus petals helped control blood sugar and improve liver and pancreas health in diabetic rats.

Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.

Gene therapy in mice increased lifespan and improved health without causing cancer.

Women with Polycystic Ovary Syndrome (PCOS) have lower levels of a substance called DIAPH1 in their blood, which is linked to changes in sugar metabolism and insulin resistance.

Oxidative stress plays a significant role in alopecia areata, and new treatments may include JAK inhibitors and antioxidants.

More high-quality research is needed to recommend flavonoids and saponins for clinical use.

Special gels help heal diabetic foot sores and reduce the risk of amputation or death.

The document reports the 19th global case of a rare skin condition in a patient from Colombia.