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Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Glutathione helps Arabidopsis roots adapt to low phosphate by regulating a specific growth pathway.

Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Cysteine helps maintain keratin production in skin cells even when iron is low.

Taurine might help prevent hair loss caused by stress.

Natural volatiles and essential oils have health benefits and can enhance the effects of some medicines, but more research is needed to understand how they work and their possible side effects.

Arabidopsis PCaP2 helps plants survive drought by linking ABA and SA signals.

The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.

PRX102 is essential for rice root hair growth by helping transport substances to the tips.

Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.

Jujube fruit extract may reduce kidney damage from ibuprofen in rats.

Mutations in the enzyme don't significantly change how it binds to its specific substances.

Hesperidin protects rat testicles from finasteride damage and improves sperm health.

Sulforaphane from broccoli can help protect skin from sun damage.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

Colchicine can inhibit hair growth by affecting cell activity and protein expression in hair follicles.

Some chemicals absorbed through the skin can cause serious health problems.

Elevated CO2 can lessen the negative impact of water shortage on soybean roots and affects specific genes.

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.

Lepidium sativum seed extracts helped reduce inflammation and improve insulin response in obese rats on a high-fat diet.

AHCC reduces hair loss and liver injury caused by chemotherapy in rodents.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Caffeic acid helps protect rats from the harmful effects of acrylamide.

Understanding drug interactions, side effects, and patient-specific factors is crucial for effective dermatological care.

People with a common type of hair loss have higher stress levels in their body, and treatments that reduce this stress could help.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

Actinic keratosis can lead to skin cancer, is more common in fair-skinned people, and can be reduced with sunscreen and treated effectively.

DHEA affects various tissues by interacting with multiple receptors and can be converted into sex hormones.