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    Glossary Glutathione Peroxidase

    enzyme that protects cells by reducing harmful peroxides

    Glutathione Peroxidase (GPx) is an enzyme that protects cells from oxidative damage by reducing harmful peroxides, such as hydrogen peroxide, into water and oxygen. It uses glutathione as a substrate to neutralize these peroxides, playing a crucial role in maintaining cellular health and preventing damage that can lead to conditions like alopecia and other oxidative stress-related diseases.

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    1. 4-hydroxynonenal, a lipid peroxidation product, inhibits glutathione peroxidase: Protective effect of glutathione Pathophysiology · 1998
    2. Assessment of Zinc and Copper Contents in Scalp Hair and Serum and Superoxide Dismutase, Glutathione Peroxidase and Malondialdehyde in Serum of Androgenetic Alopecia and Alopecia Areata Patients Medical journal of Tabriz University of Medical Sciences and Health Services · 2011 · 4 citations
    3. Antioxidants and lipid peroxidation status in the blood of patients with alopecia Cell biochemistry and function · 2000 · 55 citations
    4. Selenium as an element in the treatment of ovarian cancer in women receiving chemotherapy Gynecologic oncology · 2004 · 127 citations
    5. Antioxidants in dermatology Anais Brasileiros de Dermatologia · 2017 · 86 citations
    6. Suppression of uterine and placental ferroptosis by N-acetylcysteine in a rat model of polycystic ovary syndrome Molecular Human Reproduction · 2021 · 53 citations
    7. Melatonin promotes secondary hair follicle development of early postnatal cashmere goat and improves cashmere quantity and quality by enhancing antioxidant capacity and suppressing apoptosis Journal of Pineal Research · 2019 · 46 citations
    8. Investigation of oxidative stress in patients with alopecia areata and its relationship with disease severity, duration, recurrence and pattern Clinical and experimental dermatology · 2014 · 35 citations
    9. Improved fetal hair follicle development by maternal supplement of selenium at nano size (Nano-Se) Livestock science · 2011 · 18 citations
    10. Patients with vitiligo present fewer cardiovascular risk factors: results from a case–control study Journal of the European Academy of Dermatology and Venereology · 2011 · 17 citations
    11. Soil, grain and water chemistry and human selenium imbalances in Enshi district, Hubei Province, China 1996 · 16 citations
    12. Alterations of plasma antioxidants and mitochondrial DNA mutation in hair follicles of smokers Environmental and Molecular Mutagenesis · 2002 · 12 citations
    13. Biomarkers of selenium status in dogs BMC veterinary research · 2016 · 11 citations
    14. Oxidative Stress in Alopecia Areata and its Association with Disease Severity, Treatment and Autoimmunity Turkiye Klinikleri Journal of Medical Sciences · 2015 · 3 citations
    15. Effects of diet supplementation with sodium selenite and selenium-enriched in puppies’ health performance from post-weaning to adulthood Animal feed science and technology · 2021 · 1 citations
    16. The role of reactive oxygen species in the pathogenesis of alopecia areata: a systematic review and meta-analysis. Skin Pharmacology and Physiology · 2025
    17. Increasing GSH-Px Activity and Activating Wnt Pathway Promote Fine Wool Growth in FGF5-Edited Sheep Cells · 2024
    18. selenium and systemic lupus erythematosus (SLE): A double- blind randomised controlled trial Research Square (Research Square) · 2024
    19. Evaluation Of Oxidative Stress On Dogs With Demodicosis Turkish journal of veterinary research · 2022
    20. Biomarker of Oxidative Stress in Premature Hair Graying at Young Age Open Access Macedonian Journal of Medical Sciences · 2021
    21. Measurement of level of vitamin D and Antioxidants in Discoid Lupus Erythematosus patients Egyptian Journal of Radiation Sciences and Applications · 2018
    22. Preliminary data on biomarkers for selenium status in dogs 2015
    23. Effects of Dietary Vitamin A Level on Growth Performance,Fur Quality,Vitamin A Deposition,Serum Biochemical Indices and Antioxidant Function of Growing Rex Rabbits Dongwu yingyang xuebao · 2014
    24. Influence of Chronic Restraint Stress on Anagen Stage in Skin of Mouse Zhongguo linchuang xinlixue zazhi · 2012
    25. SELENIUM 2010
    26. Effect of human hair keratin on the function of rat liver,renal,heart and hematology profile Basic & Clinical Medicine · 2006
    27. Australasian Society for Dermatology Research Meeting, May 2006 Journal of Investigative Dermatology · 2007
    28. Protective role of agomelatine via modulation of TLR4/NF-κB: NLRP3/IL-1β signaling pathways in testosterone-induced benign prostatic hyperplasia in rats Naunyn-Schmiedeberg s Archives of Pharmacology · 2025
    29. Effect of melatonin on oxidative stress markers in patients with alopecia areata ˜Al-œMağallaẗ al-ʻirāqiyyaẗ li-l-ṣaydalaẗ · 2005 · 1 citations
    30. PRX102 Participates in Root Hairs Tip Growth of Rice Rice · 2023 · 1 citations