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Skin problems in PCOS, like excess hair, acne, and hair loss, may not always indicate high male hormone levels and need careful diagnosis for proper treatment.

Extracts from three Polynesian plants were found to promote hair growth by affecting cell growth and gene expression related to hair.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

Women with moderate body hair have higher levels of certain hormones and may benefit from treatment that increases sex hormone-binding protein.

Women with a certain type of tumor had higher levels of pregnancy hormone and male hormones, which decreased after treatment.

The document suggests new ways to assess and diagnose hyperandrogenism to improve accuracy.

Hirsutism is mainly caused by high androgen levels or sensitivity, with PCOS being the most common cause.

Certain gene variations in AKT2 are more common in women with PCOS and are linked to higher levels of specific hormones and symptoms.

Peps help Arabidopsis plants grow more root hairs by affecting specific genes and calcium signaling.

Gene variant linked to prostate cancer, hormone levels, and hair loss.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Most women referred for excess male hormone symptoms had polycystic ovary syndrome (PCOS), with other conditions being less common.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

Finasteride doesn't effectively treat hair loss in postmenopausal women.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Sebocytes play a key role in controlling androgen levels in human skin.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Different types of polycystic ovary syndrome (PCOS) have varying severity, with Type I being the most severe and common.

The study found that Frontal Fibrosing Alopecia affects a broader age range of women and early treatment can help stop hair loss.

Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.

Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.

Stem cells from hair follicles can safely treat hair loss.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.

Finasteride effectively reduces hair loss by decreasing androgen levels.

The current methods for diagnosing polycystic ovary syndrome are too vague and may lead to misdiagnosis and problems in research.