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Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Hirsutism is excessive hair growth in women often caused by polycystic ovarian syndrome, and identifying the cause is important for managing associated health risks.

Low IGF-1 and high HDL cholesterol levels are linked to more hair loss in middle-aged women.

Hirsutism causes significant psychological distress in women.

Effective hirsutism management requires identifying the cause, combining new and traditional treatments, and setting realistic expectations for patients.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Aloe Vera gel helps heal skin, treats skin conditions, and can stimulate hair growth due to its various healing properties.

Different types of PCOS need specific diagnosis methods and treatments.

Wet cupping blood has different components than regular venous blood, which might affect skin disorder treatments.

Skin symptoms can indicate endocrine disorders and have various treatments.

Older people tend to have higher biotin levels, which are weakly linked to certain blood components and negatively linked to triglycerides; biotin should be checked in patients with high triglycerides or medication-related skin issues, and only supplemented if deficient. Vitamin D and folate deficiencies are linked to specific skin conditions.

Certain gene variations in AKT2 are more common in women with PCOS and are linked to higher levels of specific hormones and symptoms.

The conclusion is that hirsutism should be diagnosed and treated because it affects quality of life and may signal other health problems.

Vegetarians should take B vitamin supplements to avoid health issues.

Metformin is less effective in men with early-onset hair loss.

Hormones are crucial for regulating body functions and imbalances can lead to health issues.

Indian women with PCOS from Delhi and Srinagar show different symptoms, with Delhi women having higher obesity and blood sugar issues, and Srinagar women showing more hair growth and testosterone levels.

Chromium salts may help with insulin sensitivity in PCOS, but more research is needed to confirm their overall effectiveness and safety.

Eicosanoids are crucial for skin health, and targeting their pathways may help treat skin conditions.

Postmenopausal women with hyperandrogenism didn't have better metabolic health even after their testosterone levels became normal.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

Women also use 5α-reductase inhibitors, and their effects differ from men.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

The research suggests that the global distribution of PCOS is likely due to historical human migration and that genes affecting PCOS may have different impacts on males and females.

The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.

Piezoelectric Nanogenerators are promising for non-invasive health monitoring but need efficiency and durability improvements.

Hidradenitis suppurativa may be related to hormones and patients often have metabolic disorders; more research is needed to understand this connection.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.