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Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

The document explains how male reproductive hormones work and affect the body.

The document concludes that managing skin conditions during pregnancy is important and requires specialized care.

The vitamin D receptor can work without its usual activating molecule.

IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.

Researchers found a way to grow cashmere goat hair cells in a lab and discovered that certain conditions improve these cells' growth and characteristics.

Stem-cell therapy shows promise for skin conditions but needs more research.

PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.

Vitamin D is important for bones, hair, blood pressure, and breast development.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

Targeting the Smoothened receptor shows promise for treating certain cancers.

The research confirms that Hidradenitis Suppurativa is characterized by increased inflammation, disrupted skin cell organization, and abnormal metabolic processes.

Spironolactone improved cognitive performance and early sleep quality but not manic symptoms, appetite, or body weight in bipolar disorder when added to sodium valproate.

Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

Bone marrow-derived stem cells improved healing and reduced scarring in second-degree burns in rats.

Foxp3+ Regulatory T Cells are important for immunity and tolerance, affect hair growth and wound healing, and their dysfunction can contribute to obesity-related diseases and other health issues.

Hormone imbalance is linked to Hidradenitis Suppurativa, a skin condition, and treatments like anti-androgenic therapy and metformin can help. It's also suggested to check patients for insulin resistance and Polycystic Ovary Syndrome.

Stem cells from hair follicles in a special gel show strong potential for bone regeneration.

Oxidative stress and immune dysfunction are linked to both Hashimoto's thyroiditis and polycystic ovary syndrome, with diet and specific treatments important for managing these conditions.

Early hormones shape sex-specific differences in rat glands.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

Plant extracts may help prevent or reverse hair graying.

Manipulating cell cleanup processes could help treat hair loss.

The skin acts like an endocrine organ, producing hormones that affect various body functions and skin health, and understanding this can lead to new treatments.

Trapa bispinosa Roxb. extract may help reduce prostate size and cell growth in BPH.

DHT, a testosterone byproduct, causes male pattern baldness.

Steroidogenic isoenzymes may help improve treatments for common hair loss.