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The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

Androgens slow hair growth by altering Wnt signaling in balding cells.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Stress can worsen skin conditions by affecting hormone levels and immune response.

Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

Prolactin slows down hair growth in mice.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

Androgens prevent hair growth by changing Wnt signals in cells.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Minoxidil boosts hair growth by triggering growth factor release from specific stem cells.

The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.

Early diagnosis and treatment are crucial for preventing permanent hair loss in various scalp conditions, and while new treatments are promising, more research is needed to evaluate their effectiveness.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Stress in mice delays hair growth and treatments blocking substance P can partly reverse this effect.