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September 1987 in “JAMA” IL-2 treatment causes skin eruptions and other reversible side effects, and may play a role in psoriasis.
122 citations,
May 2010 in “Plant Physiology” Different PIN proteins affect plant root hair growth by changing how auxin is transported.
122 citations,
July 2005 in “The FASEB journal” Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.
121 citations,
November 2020 in “Endocrine” Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.
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November 2014 in “Biological Reviews” The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.
119 citations,
January 2012 in “Nutrition & Metabolism” Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.
118 citations,
April 1998 in “Dermatologic Clinics” Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.
116 citations,
April 2002 in “American journal of veterinary research” Trilostane effectively and safely treats dogs with pituitary-dependent hyperadrenocorticism, improving symptoms and adrenal gland size.
116 citations,
May 1992 in “The American Journal of Medicine” Flutamide rarely causes liver toxicity in prostate cancer patients.
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March 2018 in “PLOS Medicine” Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.
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July 2020 in “Communications biology” Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.
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March 2018 in “Biological reviews/Biological reviews of the Cambridge Philosophical Society” Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.
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October 2007 in “Journal of pineal research” Melatonin helps regulate hair growth and protects the hair follicle from stress.
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December 1998 in “The Journal of Dermatology” Manipulating the catagen and telogen phases of hair growth could lead to treatments for hair disorders.
108 citations,
October 2009 in “Javma-journal of The American Veterinary Medical Association” Foals with Rhodococcus equi infection often have other health problems that lower their chances of survival.
108 citations,
July 2004 in “American Journal of Pathology” Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.
107 citations,
September 2002 in “Journal of Investigative Dermatology” Researchers found that hair shedding happens mostly when new hair is growing and involves a unique process.
106 citations,
January 2016 in “Journal of Cosmetic Dermatology” Using platelet-rich plasma with microneedling works better for acne scars than microneedling with water.
106 citations,
April 2010 in “ACS Nano” C60 fullerenes can alter protein function and may help develop new disease inhibitors.
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August 2010 in “Pharmacology & therapeutics” Formyl-peptide receptor agonists could be new anti-inflammatory drugs.
104 citations,
January 2005 in “Climacteric” Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.
104 citations,
May 2003 in “Endocrinology” Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.
103 citations,
June 2006 in “British journal of sports medicine” The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.
101 citations,
July 2020 in “Dermatologic therapy” COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.
101 citations,
January 1997 in “Journal of Investigative Dermatology Symposium Proceedings” Nerves and chemicals in the body can affect hair growth and loss.
101 citations,
November 1992 in “Archives of Dermatology” Steroids help hair regrowth, and minoxidil slows post-steroid hair loss, but effects are temporary.
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July 2014 in “Trends in Molecular Medicine” Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.
98 citations,
December 2008 in “Journal of Investigative Dermatology” Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.
97 citations,
March 2009 in “Dermato-endocrinology” Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.
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November 1986 in “Journal of Steroid Biochemistry” Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.