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Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.

The guideline refines PCOS diagnosis, promotes a healthy lifestyle, reviews treatments, and stresses long-term follow-up.

Gut flora changes could potentially indicate depression, but more research is needed.

Women with Polycystic Ovary Syndrome (PCOS) have a higher risk of developing type 2 diabetes due to insulin resistance.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

*Acorus calamus* has many medicinal benefits but needs more safety research.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

The Polish medical societies have redefined metabolic syndrome and recommend lifestyle changes, certain medications, and possibly bariatric surgery for treatment. They also discuss managing related health conditions.

PCOS is a common hormonal disorder in women that can lead to various health issues and requires comprehensive management.

Recognizing rare causes of MASLD is crucial for effective treatment and preventing complications.

PCOS treatment focuses on lifestyle changes and specific medications to manage symptoms and complications.

Effective PCOS treatments require targeting specific signaling pathways.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Modern skin cancer treatments can cause skin side effects and hair loss, affecting patients' quality of life.

Tirzepatide might help manage PCOS in obese patients but needs more research to confirm safety and effectiveness.

Noni fruit extract, specifically the FEA-3 sub-fraction, can increase hair growth and reduce baldness in male rabbits, potentially acting like common hair loss treatments.

Drug repositioning is a promising way to quickly develop new treatments, especially for rare diseases.

Probiotics show promise for health benefits but need more research to understand how they work.

Obesity is linked to various skin conditions and issues, and losing weight can improve these conditions.

Neurotoxins can affect neurotransmitter release and have potential in treating muscle, pain, and cancer conditions, but more research is needed on how they work.

Bariatric surgery improves ovulation rates in women with PCOS and obesity better than medical therapy.

MicroRNAs could be key biomarkers and therapeutic targets for PCOS.

Mitochondrial dysfunction links metabolic syndrome and inflammatory skin diseases, suggesting targeted therapies and lifestyle changes.

The 2024 guideline updates recommendations for genetic testing, imaging, and sperm retrieval in male infertility.

Insulin resistance increases the risk of developing type 2 diabetes and other health issues.

New drugs for heart disease may be developed from molecules secreted by stem cells.