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A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Steroids stop hair growth temporarily but don't block the signals that start it.

Measuring androstanediol glucuronide in blood is useful for assessing and tracking treatment in women with excessive hair growth.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Liraglutide caused significant weight loss in some obese women with PCOS, especially those with severe obesity and insulin resistance.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Women with PCOS have lower ghrelin levels and a weaker response to sugar, which might affect their feeling of fullness and lead to overeating.

Reconstructed skin models are useful for studying how skin processes certain chemicals.

Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Mice skin has components that could help with hair growth and might be used for diabetes treatment.

Retinoic acid, glucocorticoids, and IGF1 increase IGFBP-3 production in human dermal papilla cells, affecting hair growth.

Eating glucoraphanin can help prevent psychosis in offspring whose mothers had immune system activation.

The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.

Thioredoxin reductase 1 does not affect glucocorticoid receptor activity in hair follicle cells.

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

The study concluded that three enzymes are important for plant development by affecting sugar composition and calcium binding in plants.

Glutathione helps Arabidopsis roots adapt to low phosphate by regulating a specific growth pathway.

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

Taking riboflavin and eating less lysine can help some people with a specific genetic disorder avoid brain damage.

Hair follicle bulge cells don't help skin regrow after glucocorticoid damage; interfollicular epidermis cells do.

The oral glucose tolerance test is effective in detecting abnormal glucose tolerance in Indian women with PCOS.

The N363S gene variant does not cause higher adrenal androgen levels in women with polycystic ovary syndrome.

High glucocorticoids cause pancreatic malfunction and malabsorption, reversible with enzyme supplements.

Demodicosis should be considered in cats with facial skin issues exposed to inhalant glucocorticoids.

Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.