19 citations,
December 2019 in “Steroids” Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.
5 citations,
May 2018 in “Therapeutic advances in drug safety” Androgen use may increase the risk of stroke, but more research is needed.
106 citations,
March 2014 in “BioEssays” We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.
293 citations,
November 2011 in “Nature” The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.
1 citations,
October 2022 in “Annual review of cell and developmental biology” The nervous system helps control stem cell behavior and immune responses, affecting tissue repair and maintenance.
January 2014 in “Springer eBooks” Inflammasome proteins can indicate the severity and treatment response of various diseases and injuries.
Icosapent ethyl may help treat long-lasting symptoms after COVID-19.
163 citations,
March 2012 in “BMC biology” Stem cell niches support, regulate, and coordinate stem cell functions.
34 citations,
November 2010 in “Development” Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.
7 citations,
November 2010 in “Genesis” Mouse Scube3 affects teeth, tongue, vibrissae, and eye development, but not facial structure or limb growth.
3 citations,
April 2022 in “Frontiers in Physiology” Ptch2 plays a key role in controlling stem cell function and the ability to regenerate after birth.
1 citations,
January 2024 in “Pharmaceuticals” A new carrier improves skin delivery of tofacitinib for treating inflammatory skin diseases.
76 citations,
March 2005 in “Cancer Research” Doxorubicin can block blood vessels from hair follicles, reducing skin tumor growth.
212 citations,
August 2004 in “Proceedings of the National Academy of Sciences” Hair follicle cells can create new blood vessels in the skin.
28 citations,
November 2018 in “Journal of Cellular and Molecular Medicine” CXXC5 is a protein that controls cell growth and healing processes, and changes in its activity can lead to diseases like cancer and hair loss.
154 citations,
November 2017 in “Development” Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.
249 citations,
April 2002 in “The FASEB journal” Human skin can make serotonin and melatonin.
September 2013 in “Regenerative Medicine” γδ T cells help with hair growth during wound healing in mice.
January 2025 in “Cell Communication and Signaling” CXXC5 can both suppress and promote cancer, making it a complex target for treatment.
29 citations,
January 2020 in “Frontiers in endocrinology” Fibrodysplasia ossificans progressiva is a rare genetic disorder that causes extra bone growth and symptoms of premature aging.
36 citations,
March 2011 in “Nature Communications” Cells from a skin condition can create new hair follicles and similar growths in mice, and a specific treatment can reduce these effects.
Proper niche formation in Drosophila requires Slit-Robo signaling for cell migration.
36 citations,
September 2009 in “Journal of Cellular and Molecular Medicine” New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.
3 citations,
December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.
75 citations,
September 2017 in “Developmental biology” The circadian clock influences the behavior and regeneration of stem cells in the body.
71 citations,
January 2012 in “PloS one” The conclusion is that genetic differences affect how the cochlea heals after hair cell loss, which may challenge the creation of hearing loss treatments.
1 citations,
January 2024 in “International journal of molecular sciences” TRPV4 helps cells repair tissue and reduce scarring by controlling calcium levels.
10 citations,
December 2017 in “Chemosphere” Bisphenol-A (BPA) increases connections between brain cells and boosts their activity, but it blocks the effects of a male hormone on brain cell plasticity.
July 2023 in “Journal of Biomedical Science” Different people show different symptoms for genetic diseases because of how sensitive their bodies are to small changes in important factors.
44 citations,
April 2017 in “Genes & development” Scientists found cells in hair that are key for growth and color.