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This study found that the co-ablation of C/EBPalpha and C/EBPbeta in adult mouse skin disrupted sebocyte differentiation and epidermal homeostasis, highlighting their critical roles in these processes.

In this study, CD44 expression was absent in alopecia areata-affected scalp, with some patients regaining expression after treatment despite no significant hair regrowth, suggesting involvement in the disease's pathogenesis.

In this animal study, researchers found that the simultaneous deletion of ERBB2 and ERBB3 in mice results in impaired skin differentiation, inflammation, and sebaceous gland alteration, leading to skin lesions, while highlighting potential side effects in cancer therapies targeting these receptors.

The document concludes that scalp health is influenced by complex factors affecting sebaceous glands, including hormones, aging, and various substances.

This article reviews the discovery and various physiological effects of cyproterone acetate, reporting its established indications for several androgen-driven conditions but providing no new clinical data.

This review discusses the current state of research on skin organoids, highlighting their potential for replicating complex skin structures and comparing recent studies on stem cell microenvironments.

This study observed that during the postnatal development of gray short-tailed opossums, skin transitions from facilitating gas exchange through a dense capillary network at birth to supporting thermoregulation, with significant changes in skin thickness and structure occurring by 35 days old.

This study demonstrates that human skin is capable of steroid hormone synthesis, but its role in androgenic skin disorders like acne and alopecia is yet to be clarified.

This study suggests that programmed cell death plays a crucial role in shaping the structure of the human epidermis and its appendages during development.

This review explores the novel roles of white adipose tissue in tissue homeostasis and regeneration, emphasizing its impact on epithelial, muscle, and immune tissues, and reports no new clinical results.

The study concluded that fatty acid transport protein 4 in epidermal keratinocytes is crucial for maintaining normal skin structure, as its deficiency led to hyperkeratosis and epidermal barrier disruption in mice.

This study introduced Scd3-Cre mice, which enabled sebocyte-specific manipulation, revealing that sebaceous lipid depletion impaired water repulsion, thermoregulation, and the ocular surface, resembling Meibomian gland dysfunction.

This study found that TRPV3 activation in human sebocytes inhibits lipid synthesis and triggers proinflammatory cytokine expression, suggesting a role in the pathogenesis of dry skin-associated inflammatory dermatoses.

In this study, OCT showed strong nuclear binding in certain skin cells, suggesting similar genomic effects to vitamin D with potential therapeutic benefits due to its lower calcaemic effect.

This review of seborrheic dermatitis highlights the role of complex immunoinflammatory processes in its pathogenesis and discusses emerging treatments, such as PDE4 inhibitors, JAK inhibitors, and microbiome-targeted therapies, which may benefit patients with severe or treatment-resistant forms, according to the authors.

This review discusses the diagnosis of canine hypothyroidism, focusing on its clinical signs, diagnostic markers, and distinctive skin biopsy findings, but reports no new research results.

This review summarizes the roles of matricellular proteins in skin stem cell niches, highlighting their contribution to stem cell fate, self-renewal, and potential implications for wound healing and aging.

This review discusses the crucial role of sex hormones in maintaining and influencing skin health, suggesting ongoing research into hormonal treatments for skin conditions due to life stage changes.

Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.

This study reports that a new artificial skin system using multi-layered hydrogels can promote scarless wound healing and regenerate appendages like hair follicles without cell transplantation.

In this study, researchers identified the antimicrobial peptide dermcidin in sebocyte lipid droplets, challenging the previous understanding of dermcidin as exclusively sweat-specific.

In this study, the authors reviewed the importance of a polyherbal hair oil containing ingredients like Amla and Neem, evaluated for properties like pH and viscosity, but effectiveness for treating hair issues such as dandruff and baldness is not reported.

This article reviews current strategies and advancements in regenerating skin appendages and sensory nerves in tissue-engineered skin, highlighting the challenge of restoring skin sensations like pain, temperature, and touch to improve patients’ quality of life.

This study found that UV-B exposure significantly increased the expression of inflammatory cytokines IL-1β and IL-8 in cultured sebocytes.

This review discusses the mechanisms of skin barrier impairment in acne vulgaris and suggests strategies for its repair but reports no new clinical results.

This study surveyed individuals and found that awareness and understanding of thyroid disorders, particularly symptom recognition and the importance of early detection, are low, highlighting the need for targeted public health initiatives to improve knowledge and management.

In this study, researchers prepared a poly herbal hair oil using fresh plant leaves, including neem, and reported that these herbal formulations exhibit effective hair growth with fewer side effects compared to synthetic alternatives.

Androgens and other hormones affect hair growth and skin conditions like acne.

Cortisone may help hair regrow by altering the local environment, with regrowth starting 3-4 weeks after treatment, but its use is not widely recommended.

This study found that removing PPARγ specifically from mouse adipose tissue led to severe fat loss, insulin resistance, diabetes, and associated metabolic abnormalities.