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Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

The protein aPKCλ is crucial for keeping hair follicle stem cells inactive and for hair growth and regeneration.

Certain mature cells in mouse lungs can turn back into stem cells to aid in tissue repair.

β-catenin is essential for stem cell activation and proliferation in hair follicles.

Human skin can make serotonin and melatonin, which help protect and maintain it.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Different types of skin cells play specific roles in development, healing, and cancer.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Androgens can both increase and decrease hair growth in different parts of the body.

New effective scar treatments are urgently needed due to the current options' limited success.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.

Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.

Some common medications can harm male fertility, but many effects can be reversed.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Finasteride reduces hair loss and treats BPH without major hormone changes, but may cause sexual dysfunction.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

Hair follicles in people with alopecia have lower levels of a key blood vessel growth protein.

The vitamin D receptor is essential for skin stem cells to grow, move, and become different cell types needed for skin healing.

Foxi3 expression in developing teeth and hair is controlled by the ectodysplasin pathway.

Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.