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The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Bcl-2 overexpression protects against UVB damage but worsens hair loss from chemotherapy.

ICAM-1 helps regulate hair growth cycles and skin remodeling.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

PI3K/Akt pathway is crucial for hair growth and regeneration.

Delta-opioid receptors affect skin cell circadian rhythms, possibly impacting wound healing and cancer.

Mice without the vitamin D receptor gene lose hair due to disrupted hair follicle cycles.

HSPGs help control stem cell behavior, affecting hair growth and offering a target for hair loss treatments.

Some skin conditions may increase the risk of heart disease, and understanding their connection could lead to better treatments.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

Finasteride may affect PNMT, causing side effects.

Organotypic culture systems can grow skin tissues that mimic real skin functions and are useful for skin disease and hair growth research, but they don't fully replicate skin complexity.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

More research is needed to understand how testosterone is maintained in adult males.

Agaricus subrufescens improves ovarian function and biochemical health in rats with PCOS.

Aging in hair follicle stem cells leads to hair graying, thinning, and loss.

Dermatologists can help detect and manage eating disorders by recognizing skin changes.

Type XVII collagen helps control skin cell growth and could be a target for anti-aging treatments.

A new model using mice with human hair follicles helps better understand hair loss from chemotherapy.

Combination therapies for androgenetic alopecia work best but can have significant side effects and costs.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Fish oil improves skin health in people with diabetes and high cholesterol.

RF-based therapies might help treat hair loss.

New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

Lack of sleep in mice leads to prostatitis by reducing certain hormones and activating an inflammatory pathway, which can be temporarily fixed with normal sleep.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

SHBG binding properties are unchanged in male liver cirrhosis patients.