June 2024 in “Computational and Structural Biotechnology Journal” This review discusses the integration of omics analyses in androgenetic alopecia research, reporting no new clinical results but suggesting that collaborative multi-omics studies may enhance understanding of AGA's pathomechanisms.
February 2025 in “Geriatrics and gerontology international/Geriatrics & gerontology international” This study found that cataracts, hair changes, short stature, and low bodyweight are key indicators for diagnosing Werner syndrome in patients under 30, differing from older age group symptoms.
This study found that iontophoresis significantly increased folicular delivery of minoxidil sulfate and sustained release when combined with chitosan microparticles, suggesting potential to reduce application frequency for treating androgenic alopecia.
104 citations
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May 2003 in “Endocrinology” This study found that the vitamin D receptor in lampreys, which lack bones and hair, binds 1,25-dihydroxyvitamin D3 and may function to induce enzymes for detoxifying substances.
12 citations
,
December 2017 in “Food and chemical toxicology” This study found that mixtures used in permanent hair dyes had irritant effects on reconstructed human epidermis, while individual ingredients alone did not.
June 2025 in “Proceedings of the National Academy of Sciences” In this study, a mouse model with a PIK3CA gain-of-function mutation in Schwann cells revealed unique communication with neighboring cells and a glycolytic shift in peripheral nerves, and early alpelisib treatment significantly improved symptoms, though efficacy declined with delayed administration due to limited drug penetration.
38 citations
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February 2012 in “British Journal of Dermatology” This study suggests that the AR/EDA2R locus may contribute to early-onset female pattern hair loss, but no association was found with the 20p11 locus.
30 citations
,
November 2000 in “British Journal of Cancer” This study found that certain endocrine factors, influenced by smoking, birth order, and frequency of orgasms, may play an important role in the development of male breast cancer.
26 citations
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September 2023 in “Bioengineered” This review article discusses recent progress in the extraction and potential health benefits of oligosaccharides from brown seaweeds, especially focusing on their antimicrobial, anti-inflammatory, and prebiotic properties, and possible applications in managing metabolic syndrome.
24 citations
,
July 1998 in “Journal of the South African Veterinary Association” In this study, persistent ringworm infections in dairy calves appeared resistant to standard topical treatments and showed a potential risk of spreading to human attendants.
11 citations
,
October 1994 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride increases hair growth, prolongs hair cycle, and lowers dihydrotestosterone levels.
8 citations
,
February 2022 in “Journal of Clinical Medicine” This study found that a notable percentage of COVID-19 patients experienced post-infection telogen effluvium, although no significant associations with infection-related factors were identified.
6 citations
,
May 2024 in “PLoS ONE” In this study, content analysis of German YouTube videos revealed that women frequently experience both positive and negative symptoms related to oral contraceptive use and discontinuation, with bodily sensations often influencing their decisions to start or stop the pill.
6 citations
,
January 2000 in “The Journal of Trace Elements in Experimental Medicine” In this study, an 11-year-old girl with acrodermatitis enteropathica showed significant improvement in symptoms after oral zinc therapy.
1 citations
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April 2023 in “Biomolecules” This study found that hair care products containing fermented papaya, fermented mangosteen, and caffeine significantly inhibited hair loss, increased hair density and thickness, and improved hair follicle structure in individuals with androgenic or diffuse alopecia over three months compared to placebo and caffeine controls.
September 2025 in “Pakistan Journal of Science” This study observed that individuals with type 1 diabetes mellitus have notably lower levels of essential and trace elements like Calcium, Potassium, and Zinc in biological samples compared to non-diabetic controls.
January 2000 in “The Journal of Trace Elements in Experimental Medicine” In this case report, an 11-year-old girl with acrodermatitis enteropathica experienced a complete resolution of symptoms following oral zinc therapy, highlighting its effectiveness in managing this condition.
155 citations
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December 2003 in “British Journal of Dermatology” In this study, the researchers did not confirm previously reported links between AGA and smoking or benign prostatic hypertrophy, but found potential associations with alcohol consumption and lean body mass at age 21 that merit further investigation.
106 citations
,
March 2013 in “Nature Communications” This study found several microRNA-related genetic variants linked to epithelial ovarian cancer risk, with a notable association at the 17q21.31 region, suggesting potential new susceptibility genes.
101 citations
,
March 2019 in “Cell Stem Cell” This study found that Oncostatin M, via JAK-STAT5 signaling, keeps hair follicle stem cells inactive, and its removal leads to hair growth initiation in mice.
81 citations
,
July 2008 in “The Journal of Clinical Endocrinology and Metabolism” This study found that cortisone reductase deficiency is caused by inactivating mutations in the H6PD gene, affecting cortisol metabolism by preventing 11β-HSD1 enzyme function.
64 citations
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March 2017 in “Nature communications” This study identified 63 genetic loci associated with male-pattern baldness, uncovering genes and pathways that may help develop treatments and suggesting its connection to other human conditions.
44 citations
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March 2020 in “Antibiotics” The researchers reported that carnosic acid and carnosol, extracts from rosemary leaves, specifically inhibit S. aureus virulence expression, suggesting potential topical treatments for atopic dermatitis flares.
40 citations
,
November 2021 in “International Journal of Molecular Sciences” This review highlights the role of keratin mutations in epidermolysis bullosa simplex and the resulting chronic inflammation, but it presents no new experimental findings.
25 citations
,
May 2019 in “Heliyon” This study found that excessive heat caused the most significant structural changes in hair from Caucasian and Afro samples, especially when combined with other treatments like bleaching and straightening.
24 citations
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May 2019 in “PLOS genetics” This study reports that compound heterozygous loss-of-function mutations in the HEPHL1 gene in a child were associated with abnormal hair and cognitive issues, linking altered ferroxidase activity to hair disorders.
21 citations
,
January 1999 in “Molecular and Cellular Biochemistry” Niacin deficiency makes rats more sensitive to cancer-causing chemicals.
15 citations
,
December 2017 in “Journal of Investigative Dermatology” This study identified two genome-wide significant genetic associations with seborrheic dermatitis, suggesting a potential genetic susceptibility contributing to the disease's pathogenesis.
12 citations
,
August 2019 in “BMC Medical Genetics” This study found that two MC4R gene polymorphisms are associated with higher BMI in women with PCOS in western Saudi Arabia, but are not linked to PCOS itself.
8 citations
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May 2005 in “Australian veterinary journal” This case report documents the first instance of recurrent flank alopecia in a Tibetan Terrier, diagnosed alongside atopic dermatitis.