508 citations,
February 2007 in “Cell” Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.
265 citations,
July 2012 in “Cell” The study found that sweat glands contain different types of stem cells that help with healing and maintaining healthy skin.
181 citations,
January 2009 in “Nature Genetics” Certain mutations in a hair growth-related gene cause a type of genetic hair loss.
138 citations,
June 2012 in “Genes & Development” Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.
133 citations,
May 2016 in “Cell Host & Microbe” Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.
131 citations,
July 2009 in “Experimental Dermatology” The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.
116 citations,
August 2010 in “Nature” Scientists turned rat thymus cells into stem cells that can help repair skin and hair.
52 citations,
April 2013 in “Developmental Cell” Brg1 is crucial for hair growth and skin repair by maintaining stem cells and promoting regeneration.
51 citations,
September 2020 in “Cell Metabolism” Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.
36 citations,
April 2018 in “Journal of Investigative Dermatology” Macrophages help hair growth after injury through CX3CR1 and TGF-β1.
35 citations,
September 2012 in “PloS one” Two distinct pathways direct proteins to vacuoles in Arabidopsis, affecting root hair growth and protein targeting.
31 citations,
July 2004 in “Molecular Medicine” Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.
30 citations,
October 2016 in “Current research in translational medicine” Hair follicles on the scalp interact with and respond to the nervous system, influencing their own behavior and growth.
29 citations,
March 2012 in “Stem Cell Research & Therapy” Some stem cells in the body rarely divide, which could help create better treatments for diseases and aging.
11 citations,
July 2021 in “Physiologia Plantarum” SIPHL1 from tomato enhances plants' response to low phosphate levels.
5 citations,
April 2021 in “Biomedicines” The engineered skin substitute helped grow skin with hair on mice.
2 citations,
December 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The SYP123-VAMP727 complex is important for transporting materials that harden the root hair shank in Arabidopsis.
September 2006 in “Plastic and Reconstructive Surgery” The SGAP flap effectively treats large sacral pressure sores with good results and minimal complications.
September 2006 in “Plastic and Reconstructive Surgery” Hair transplant surgeries can be improved by preserving follicles in a special solution, and surgeries done at outpatient facilities are more profitable than those at hospitals.
September 2006 in “Plastic and Reconstructive Surgery” Outpatient aesthetic and reconstructive surgeries are about equally profitable in Academic Health Centers and Ambulatory Surgery Centers when time is considered, but dedicated surgery centers are generally more profitable.
56 citations,
February 2012 in “Developmental biology” Sostdc1 controls the size and number of hair and mammary gland structures.
36 citations,
March 2014 in “Molecular and Cellular Biology” Cidea is essential for proper lipid storage and secretion in sebaceous glands, affecting skin and hair health.
21 citations,
June 2016 in “PloS one” Zebrafish need MYC and FGF to regenerate inner ear hair cells.
7 citations,
August 2022 in “Journal of Nanobiotechnology” Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.
1 citations,
June 2023 in “Reproduction” Microglia, the brain's immune cells, may contribute to Polycystic Ovary Syndrome (PCOS) by altering the female brain's structure and function, with kisspeptin neurons and GABA neurotransmitters also playing a role.
CCC1 is crucial for pH balance in plant cells, affecting growth and stress tolerance.
7 citations,
September 2013 in “Tissue engineering. Part A” Hair follicle stem cells can become motor neurons and reduce muscle loss after nerve injury.
11 citations,
October 2020 in “Plant biotechnology journal” Overexpressing SIMK in alfalfa boosts root hair growth, nodule clustering, and shoot biomass.
50 citations,
September 2014 in “Stem cell reports” BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.
8 citations,
June 2022 in “Scientific Reports” LGR5 is a common marker of hair follicle stem cells in different animals and is important for hair growth and regeneration.