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A woman's unique dementia was misdiagnosed, a genetic mutation increases Parkinson's risk with age, and finasteride may help with Tourette syndrome.

In this study, hair-follicle-associated pluripotent stem cell implantation improved functional recovery and reduced inflammation in a mouse model of intracerebral hemorrhage.

This study observed that disrupting the Pnkp gene in adult mice resulted in a premature aging-like phenotype, suggesting PNKP's vital role in maintaining normal growth and survival of certain progenitor cell populations.

This review examines glycopeptide hydrogels as biomimetic materials for tissue regeneration and other biomedical applications, describing their design, properties, and potential uses, and highlighting future advancements in replicating natural tissue environments for precision medicine.

In this study, researchers identified several active metabolites in Eclipta alba, demonstrated strong interaction with Alzheimer's disease proteins, and found that 28 days of treatment improved memory without significant toxicity in rats, suggesting potential pathways for treating Alzheimer's.

This study found that a long-term astrocyte culture model can effectively study astrocyte senescence and suggests minoxidil as a potential candidate to regulate brain aging by normalizing dysregulated gene expression in aged astrocytes.

This study observed that human dental pulp stem cells can differentiate into adipocytes and osteocytes, but their potential for neural differentiation remains uncertain due to similar responses seen in undifferentiated cells.

This study found that hair follicle stem cells are multipotent and can enhance nerve regeneration and function in mice, showing potential as an accessible source for treating peripheral nerve injuries.

This study found that nestin-expressing hair follicle-derived cells express higher levels of certain neurotrophic factors and neural markers, indicating potential for neuroregenerative therapy applications.

In this review, researchers detail how immunosenescence and chronic neuroinflammation contribute to Parkinson's disease progression, exploring potential therapeutic strategies targeting this axis, such as senolytic agents and immune rejuvenation, while highlighting associated challenges and future research needs.

This study found that Ca²⁺ signaling and peptidylarginine deiminase enzymes play a crucial role in activating neural stem cells in response to injury in zebrafish, suggesting potential therapeutic targets for CNS injuries and cancer.

This study found that preconditioning human hair follicle-derived stem cells with valproic acid enhanced their survival and migration in ischemic-like conditions by activating autophagy and inhibiting the AKT/mTOR pathway, suggesting this approach could improve stem cell therapies for ischemic stroke.

In this study, a pH-responsive microneedle patch was developed, showing potential in rat models for treating spinal cord injuries by reducing inflammation, promoting nerve regeneration, and supporting neurogenesis, which contributed to improved motor and neurological recovery.

This study found that Spirulina algae extract significantly increased the differentiation of bone marrow-derived mesenchymal stem cells into neural cells without toxicity, suggesting potential as a therapeutic approach for neurodegenerative diseases in an in vitro setting.

This case report details a rare instance of a young male with coexisting autoimmune polyendocrine syndrome type 2 and anti-GAD65 antibody-associated stiff person syndrome, where symptoms improved by adding intravenous immunoglobulin therapy, emphasizing the importance of awareness for early diagnosis and treatment.

Among adult male rats, this study found that combined exposure to lithium carbonate and lead acetate over 28 days led to synergistic cardiotoxic effects, evidenced by oxidative stress, ECG abnormalities, and molecular markers of increased apoptosis, despite no observable structural damage to myocardial tissue.

This review of 355 articles found that apigenin, a compound found in many plants and vegetables, is mainly researched for its anti-inflammatory, neuroprotective, and anti-cancer properties, with enhanced efficacy when combined with allopathic drugs.

This study used a novel fluorescent tagging method in mice to observe collagen IV dynamics during hair follicle development, revealing that alterations in basement membrane turnover can influence epithelial progenitor cell behavior and organ morphology by affecting cell proliferation and movement.

In this study, researchers differentiated human induced pluripotent stem cells into dermal papilla-like cells and observed gene expression dynamics during five stages of dermal differentiation, demonstrating the potential of these cells to interact with epidermal cells in functional assays.

This study found that vimentin is essential for proper wound healing and cell growth by influencing EMT signaling and mTOR activity in mice.

In this study, high expression of S100A4 in glioblastoma was associated with worse patient survival and promoted tumor progression by enhancing pro-tumorigenic vascular functions.

This study found that overexpression of β-catenin in bipotent Schwann-cell precursors promotes melanocyte development in limb areas by inducing MITF and repressing FoxD3, especially during a specific developmental timeframe.

This study found that hair follicle stem cells, when transplanted in a rat model of ischaemic stroke, migrated to affected areas, expressed neuron-specific markers, and reduced infarct volume, suggesting potential therapeutic benefits.

Inflammasome proteins can indicate the severity and treatment response of various diseases and injuries.

This abstract contains only journal subscription and informational content and does not present any research findings.

This study observed that stem cells from the hair follicle dermis share similarities with bone marrow-derived mesenchymal stem cells and have potential to form neural-like cells under specific conditions.

This article discusses female pattern androgenic alopecia, emphasizing its impact on women's lives and highlighting the need for further research into effective treatments, but reports no new clinical results.

Researchers found an RNA transcript that might help control a growth factor linked to tumor development.

This study identified FP-1 as a highly specific extracellular matrix protein in follicular papilla cells, which may play a role in hair growth regulation during specific hair cycle phases.

GFC is more effective than PRP for treating hair loss.