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Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Low doses of mixed chemicals cause permanent reproductive malformations in male rats.

Treatment during development affects hormone balance and sexual behavior in male rats.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Chromium supplements don't improve insulin, hormone levels, or cholesterol in women with PCOS but raise testosterone levels.

Relatives of women with PCOS symptoms are more likely to have similar health issues.

The document recommends a team-based approach and personalized care for managing diabetes in teenagers.

Hair analysis is better than urine and blood for detecting past drug use.

Melasma is a skin condition linked to female hormones, genetics, UV exposure, and certain medications, but not to pituitary, adrenal, or thyroid diseases.

PCOS is linked to a higher risk of endometrial cancer but not ovarian or breast cancer, and more research is needed on its role in cancer development and treatment effects.

Dermatologists can help diagnose endocrine disorders like PCOS and metabolic syndrome by looking at skin symptoms.

Minoxidil is effective for hair growth and safe for long-term use.

Some plant-based treatments may help with ovary function, insulin resistance, and excess male hormones in PCOS, but more research is needed to confirm their safety and effectiveness.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

Lower SHBG levels may increase the risk of PCOS.

Eating fewer calories, less sugar and refined carbs, and more low-glycemic and omega-3 rich foods can help manage PCOS symptoms.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

Women with androgenic alopecia are more likely to have polycystic ovaries and higher androgen levels, which may indicate PCOS.

Pregnancy causes skin changes like darkening, hair thickening, nail changes, and increased risk of skin growths, most of which usually resolve after birth.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

SHBG may be a useful early indicator and treatment target for PCOS.

Metformin and rosiglitazone improve blood vessel function in women with PCOS, with metformin also reducing insulin resistance and testosterone levels.