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To diagnose Polycystic Ovarian Syndrome, two out of three signs—irregular periods, high male hormone levels, or cysts on the ovaries—are needed.

ECM molecules are crucial for hair growth and development.

Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.

Hair problems can be caused by genetics or the environment, and treatment should focus on the cause and reducing hair damage.

Genetic mutations can cause hair growth disorders by affecting key genes and signaling pathways.

Minoxidil is mostly safe, but high doses can cause electrolyte imbalances and heart issues in dogs.

Lifestyle changes are the main treatment for PCOS, which is a complex condition requiring early management to reduce its health impacts.

Women with polycystic ovary syndrome tend to have a longer distance between the clitoris and anus.

Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.

New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.

Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.

Group a wide range of chemicals, not just phthalates, for assessing risks to male reproductive health.

The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.

Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Fetal cells could improve skin repair with minimal scarring and are a potential ready-to-use solution for tissue engineering.

Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Understanding how EDC genes are regulated can help develop better drugs for skin diseases.

Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

The document concludes that treating PCOS requires a combination of drugs to manage reproductive and metabolic symptoms, with more research needed on combination therapies.

Finasteride reduces male rat fertility by causing issues with copulatory plug formation.

Sweat glands and hair follicles are structurally connected within a specific layer of skin fat.

Teriflunomide is an effective and generally safe oral treatment for relapsing MS, reducing relapses and slowing disability progression.

Eating glucoraphanin can help prevent psychosis in offspring whose mothers had immune system activation.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Fibromodulin treatment helps reduce scarring and improves wound healing by making it more like fetal healing.