12 citations
,
December 2020 in “Archives animal breeding/Archiv für Tierzucht” This study found that EDA and EDAR are expressed throughout cashmere goat fetal development and play a critical role in hair follicle formation by influencing gene expression in fibroblasts and epithelial cells.
12 citations
,
June 2020 in “Frontiers in Cell and Developmental Biology” This study found that the PP2A-B55α regulatory subunit is crucial for ectodermal development in mice, with knockout embryos displaying severe neural and epidermal defects and failing to survive to birth.
12 citations
,
May 2019 in “Stem cell reviews” In this study, fetal stem cells were identified in adult human hair follicles long after childbirth, indicating potential for autologous therapies due to their pluripotent characteristics.
12 citations
,
March 2017 in “Journal of obstetrics and gynaecology Canada” This review discusses the limitations of serum androgen measurements in diagnosing and treating women with potential androgen-related disorders and the potential role of androgen replacement therapy for those with sexual interest/arousal disorders, reporting no new results.
12 citations
,
April 2016 in “PLoS ONE” This study found that the Chinese version of the Polycystic Ovary Syndrome Quality of Life Questionnaire (Chi-PCOSQ) is sensitive to clinical changes and effectively assesses health-related quality of life in Chinese women with PCOS.
12 citations
,
January 2016 in “Endocrinology, diabetes & metabolism case reports” This report describes a 19-year-old male with 49,XXXXY syndrome receiving testosterone replacement therapy, which led to improvements in reproductive development, metabolism, and social interaction after a year of treatment.
12 citations
,
March 2015 in “Pediatric Dermatology” This review discusses diagnostic and management challenges of polycystic ovary syndrome in children and adolescents and reports no new clinical results; it emphasizes early intervention when a provisional diagnosis is suspected.
12 citations
,
September 2012 in “Alcohol and Alcoholism” This study found that a week of daily alcohol exposure during late adolescence led to a long-term increase in alcohol preference in adulthood, highlighting the sensitivity of this age group to alcohol's effects.
12 citations
,
January 2010 in “Pediatric Health” This review discusses treatment strategies for PCOS, focusing on using insulin-sensitizing medications alongside weight reduction and exercise to improve hyperinsulinemia and hyperandrogenism, and reports no new results.
11 citations
,
December 2022 in “Arterial Hypertension” This joint position paper by several Polish medical societies examines guidelines and recommendations for managing conditions like obesity, hypertension, and liver disease, underscoring the importance of a collaborative, interdisciplinary approach in treatment. Results are not explicitly reported.
11 citations
,
February 2022 in “Scientific Reports” This study found that CD26+ fibroblasts are crucial for effective extracellular matrix production and achieving rapid epidermal and dermal homeostasis in human tissue-engineered skin substitutes transplanted onto rodents.
11 citations
,
March 2020 in “American Journal of Medical Genetics Part A” This study identified a novel homozygous EDNRA variant linked to Oro-Oto-Cardiac Syndrome and showed that EDNRA signaling is essential for normal craniofacial and cardiovascular development.
11 citations
,
February 2019 in “Research and reports in forensic medical science” This article discusses the use of forensic DNA phenotyping to infer physical characteristics from biological samples without a reference sample, aiding investigations but raising ethical and legal concerns.
11 citations
,
August 2018 in “Asian-Australasian journal of animal sciences” This study found that a short daily photoperiod increased crude protein digestibility, secondary hair follicle activity, and cashmere quality in Inner Mongolia white cashmere goats without harming fiber characteristics.
11 citations
,
December 2017 in “Diabetes Therapy” This study highlights the need to prioritize early prevention of type 2 diabetes mellitus by focusing on early pathophysiologic mechanisms such as insulin resistance, rather than hyperglycemia, as conditions like non-alcoholic fatty liver disease and polycystic ovarian syndrome are early indicators of future diabetes risk.
11 citations
,
June 2017 in “Anais Brasileiros de Dermatologia” This study observed changes in dermatological disease incidence in a Brazilian town, with increases in conditions like sexually transmitted diseases and leprosy and decreases in others such as urticaria and superficial mycoses between 2003 and 2014.
11 citations
,
July 2016 in “Endocrinology” This study found that higher Lnk expression in PCOS patients may contribute to insulin resistance by inhibiting insulin signaling pathways.
11 citations
,
December 2014 in “Clinical Obstetrics and Gynecology” This article presents a systematic approach for obstetricians/gynecologists to diagnose and manage common types of nonscarring hair loss in women, reporting no new clinical results.
11 citations
,
June 2012 in “Human Reproduction Update” This review discusses recent advancements in female contraception and covers topics like adapted regimens, non-invasive sterilization, and the promise of new methods, but it reports no new clinical findings.
11 citations
,
October 2003 in “Postgraduate Medical Journal” This study described four cases of delayed diagnosis of Cushing’s syndrome, highlighting that increased clinical awareness and screening could reduce its associated morbidity and mortality.
11 citations
,
May 2003 in “Obstetrics and gynecology (New York. 1953. Online)/Obstetrics and gynecology” This review explores the evaluation and treatment of hirsutism, emphasizing a systematic approach to uncovering its causes and recommending combination therapies for effective management, but presents no new results.
11 citations
,
January 2000 in “Journal of Cutaneous Pathology” This paper reviews the role of the telomere-telomerase system in cellular ageing and cancer, discussing potential therapies but reporting no new experimental results.
11 citations
,
February 1989 in “Journal of veterinary medicine. Series A” This study observed that congenital hypotrichosis in crossbred cattle is linked to short, curly, dilute-color hair, potentially due to color dilution mutants in European breeds.
10 citations
,
November 2024 in “Cureus” This systematic review identified several factors contributing to increased cardiovascular risk in women with polycystic ovary syndrome, including insulin resistance, obesity, inflammation markers, and microbiota alterations linked to elevated trimethylamine-N-oxide levels.
10 citations
,
May 2020 in “Dermatology Research and Practice” This review discusses "follicular hypoglycania" as a potential pathology in hair growth disorders and reports that proteoglycan replacement therapy may improve hair loss treatments, though it presents no new clinical trial results.
10 citations
,
January 2019 in “The Nurse Practitioner” This article reviews diagnostic and treatment guidelines for polycystic ovary syndrome, discussing how nurse practitioners can enhance patients' quality of life through education; it reports no new clinical results.
10 citations
,
January 2017 in “Expert Opinion on Pharmacotherapy” This review discusses the clinical features and treatment options for adult acne, highlighting the need for tailored management in specific populations, but reports no new findings.
10 citations
,
January 2014 in “Endocrinology & metabolic syndrome” This review summarizes the current knowledge on polycystic ovary syndrome, including its features, diagnosis, and treatment, and highlights the need for further research to fill existing knowledge gaps.
10 citations
,
April 2013 in “Veterinary dermatology” In this study, four dogs with a novel skin disease showed clinical lesions involving verrucous, crusted papules and plaques, and responded variably to immunosuppressive therapy, suggesting an immune-mediated cause.
10 citations
,
November 2010 in “Journal of Pharmacy Practice” This article discusses polycystic ovary syndrome, highlighting treatment approaches for managing insulin resistance, hyperandrogenism, and fertility issues, but reports no new clinical results.