32 citations
,
September 2011 in “Journal of Neuroendocrinology” In this study, inhibiting the formation of 5α-reduced steroids in pregnant rats shortened gestation time, reduced litter size, and impaired cognitive and neuroendocrine function in their juvenile offspring.
1 citations
,
August 2021 in “Primary Care Diabetes” This article reviews maternal-fetal outcomes in patients with gestational diabetes and COVID-19 through a case study and literature analysis but reports no new clinical results.
January 2024 in “African Journal of Biomedical Research” In this study of pregnant women in Pampore, Kashmir, 90% were found to have hypothyroidism, with 75% of thyroid dysfunction cases being diagnosed during pregnancy. The study highlights the need for better nutrition and early screening to manage gestational thyroid dysfunction effectively.
May 2023 in “Journal of The American Academy of Dermatology” This source reports that pregnancy leads to significant changes in skin physiology, including hyperpigmentation, hair and nail alterations, vascular modifications, and glandular shifts, highlighting the complex physiological adjustments during this period.
June 2003 in “Obstetrical & Gynecological Survey” In this study, the size of vaginal prolapse was significantly linked to preoperative vaginal length and the length of vaginal excision following the Michigan four-wall sacrospinous suspension.
1 citations
,
January 2018 in “Cogent Medicine” This case study reports a pregnant woman with bullous pemphigoid who developed Cushing syndrome following steroid treatment, emphasizing the need for careful management of steroid-related complications.
49 citations
,
March 2009 in “Archives of Gynecology and Obstetrics” This study found that age, pre-pregnancy BMI, and family history of diabetes were independent predictors of gestational diabetes in Iranian women, with selective screening missing few cases among low-risk groups.
2 citations
,
May 2018 in “PubMed” In this study, pregnant women with isolated hypothyroxinemia experienced more asthenia, dry skin, hair loss, fragile nails, vomiting, and anemia, suggesting a negative impact on pregnancy despite treatment.
52 citations
,
October 2007 in “Molecular Therapy” Injecting lentiviral vectors into early gestation mice effectively targets skin stem cells for potential gene therapy.
34 citations
,
May 2013 in “Journal of the European Academy of Dermatology and Venereology” In this study, changes in hair cycle phases during pregnancy and the post-partum period showed a rise in telogen rates after delivery, especially among non-breastfeeding women, but no drastic exaggerations were noted.
1 citations
,
January 2017 in “UKnowledge (University of Kentucky)” This study found that while dutasteride significantly altered pregnane metabolism in mares during late gestation, it did not impact pregnancy outcomes, highlighting the complexity of pregnane metabolism and the necessity of LC-MS/MS for accurate measurement.
March 2024 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” In this study, supplementing ewes with soy hulls instead of a traditional corn-based supplement showed no impact on gastrointestinal nematode infection levels in hair sheep ewes managed in a pasture-based system, though some differences in packed cell volume at weaning were noted.
September 2008 in “Fertility and Sterility” This study found that pregnancies with gestational diabetes in a Midwestern U.S. cohort demonstrated elevated androgen levels compared to healthy controls, suggesting a common relationship between impaired glucose tolerance and hyperandrogenemia across diverse ethnic backgrounds.
76 citations
,
July 2009 in “Neuroscience” This study found that inhibiting allopregnanolone synthesis in late gestation fetal sheep increased apoptosis and dead cell count in the hippocampus and cerebellum, effects that were mitigated by alfaxalone co-infusion.
34 citations
,
April 1973 in “The American journal of clinical nutrition” This study found that inadequate maternal pyridoxine during pregnancy led to lower body weight, slow physical development, and impaired neuromotor development in rat pups, with the severity increasing as pyridoxine levels decreased.
9 citations
,
April 2018 in “Biology of reproduction” This study concluded that dietary changes alter serum progesterone and estradiol levels in late gestation ewes, likely due to metabolism rather than changes in placental steroid synthesis.
1 citations
,
July 2024 in “Frontiers in Pharmacology” In this study, a pregnant woman inadvertently exposed to spironolactone delivered a healthy male infant with normal genitalia, highlighting the need for more research on the safety of spironolactone and new-generation mineralocorticoid receptor antagonists during pregnancy.
March 2024 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” This study found that substituting soy hulls for corn-based supplements did not significantly affect ewe growth, reproductive performance, or lamb performance in pasture-based hair sheep systems.
January 2023 in “Brazilian Journals Editora eBooks” August 2017 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” In this study, melatonin supplementation in cattle during mid to late gestation decreased the temperature of unshaved skin areas but did not affect rectal temperature or body weight.
100 citations
,
April 2007 in “Neuroscience” This study found that treatment with finasteride in fetal sheep reduced the protective neurosteroid allopregnanolone, leading to increased cell death in the hippocampus following induced fetal asphyxia.
9 citations
,
June 2016 in “The Cerebellum” 1 citations
,
February 2023 in “Animals” In this study, the inclusion of a feedstuff high in energy along with soybean meal enhanced body condition, body mass index, and reproductive performance in sheep fed low-protein forage.
10 citations
,
August 2023 in “Clinical Nutrition” This study found that exposure to certain elements during pregnancy, measured in maternal hair, was associated with increased risk of gestational diabetes and potential impacts on infant neurodevelopment, with elements like Ta, Re, and Se posing the highest risk for gestational diabetes.
March 2024 in “Animal nutrition” This study found that sows consuming beet pulp had higher feed intake and improved litter performance during heat stress, while a high-fiber diet enhanced insulin levels, suggesting dietary fiber's importance for reproductive and metabolic health in sows.
6 citations
,
April 2024 in “Journal of Investigative Dermatology” This review highlights recent advances in CRISPR-based lineage tracing methods that can improve our understanding of skin stem cell behavior, regeneration, and disease, with potential applications in organoids and model organisms.
883 citations
,
August 2016 in “Nature Reviews Disease Primers” This review discusses the current understanding of polycystic ovary syndrome, focusing on its epidemiology, pathophysiology, diagnosis, management, and future research directions, but reports no new clinical results.
369 citations
,
June 2013 in “Biochimie” This review discusses the potential benefits of myo-inositol supplementation for insulin resistance-related disorders and diabetic complications, but reports no new clinical results.
292 citations
,
April 2024 in “Nature Reviews Disease Primers” Early diagnosis and treatment of PCOS are crucial to reduce health risks and costs.
200 citations
,
October 2009 in “European journal of endocrinology” This review discusses the multifaceted actions of metformin in polycystic ovary syndrome and reports no new clinical results; the authors emphasize metformin's potential benefits in both cardiometabolic and reproductive aspects of PCOS.