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This study identified 8-hydroxy germacrene B from Curcuma aeruginosa as a highly potent in-vitro 5-alpha reductase inhibitor with significant anti-androgenic activity, while exhibiting mild cytotoxicity on prostate cancer cells without affecting human dermal papilla cells at tested concentrations.

In this study, different drying methods for Hedychium spicatum rhizomes significantly affected the essential oil yield, antioxidant potential, and compound composition, with the HSOV30 method yielding the highest oil content, antioxidant activity, and specific compound levels such as 1,8-cineole and elemol.

This study found that co-applying Curcuma aeruginosa extract or essential oil with minoxidil significantly increased minoxidil's skin penetration in an ex vivo setting, suggesting an improved topical treatment strategy for androgenic alopecia with greater efficacy and the potential for lower minoxidil doses.

This study identified and characterized eight compounds, including furanocoumarins and pterocarpans, from the aerial parts of Bituminaria basaltica, with β-caryophyllene and germacrene D as main constituents of its essential oil.

This review of Cedrus libani highlights its potential as a source of natural antioxidants and antimicrobials and notes that it may offer analgesic and anti-inflammatory benefits; however, further toxicological and clinical studies are necessary to confirm its safety and efficacy for treating human diseases.

This study found that antiandrogenic compounds in Curcuma aeruginosa, including germacrone, degrade rapidly at high temperatures but are more stable when solubilized in PEG-40.

In this study, germacrone from Curcuma aeruginosa showed anti-androgenic effects by inhibiting 5α-reductase, suggesting its potential as a lead compound for treating androgen-dependent disorders.

This literature review compiles and analyzes current research on turmeric essential oil's active compounds, reporting their potential therapeutic applications across various medical conditions due to their unique pharmacological profiles and absence of toxicity.

This review highlights the chemical components and various potential health effects of Daucus carota but reports no new experimental results.

In this study, the researchers investigated the plant Vitex negundo and its active ingredients, noting that both natural and synthetic derivatives exhibit concentrated biological activity, which may explain the plant's traditional use in treating various ailments such as depression, malaria, and skin diseases.

This study found that undiluted mint leaf extract effectively inhibited multidrug-resistant Staphylococcus aureus and killed Culex pipiens larvae, suggesting its potential as a biocontrol strategy around hospitals.

This study explored the optimization of phytochemicals from Alstonia boonei to develop potential 5-alpha reductase inhibitors for Benign Prostatic Hyperplasia, finding promising analogs with enhanced binding affinity and stability compared to Finasteride, warranting further experimental validation.

This review discusses the therapeutic potential of costunolide for various diseases, highlighting its bioactivity and mechanisms, but it reports no new experimental results.

In this study, researchers developed a herbal shampoo using natural plant extracts, which maintained physicochemical properties and improved hair texture without the side effects commonly associated with synthetic ingredients.

This study reviewed the use of essential oils in cosmetics and highlighted that while chamomile, rosemary, and geranium oils can be applied directly to the skin when diluted, most essential oils require caution due to potential dermatological reactions.

In this study, Indonesian spices were screened in silico for their potential to inhibit MMP9 and TNFα, which are involved in chronic diabetic wounds, and procyanidin was identified as the most promising therapeutic candidate due to its low binding energy to both proteins.

This study found that a high sesquiterpene C. aeruginosa extract significantly reduced axillary hair growth in women compared to placebo with no apparent adverse effects.

This study found that a combination of 5% hexane extract of Curcuma aeruginosa and 5% minoxidil slowed hair loss and increased hair growth in men with androgenetic alopecia.

In this study, applying 1% or 5% Curcuma aeruginosa essential oil lotion to the underarm for 10 weeks significantly slowed hair growth and brightened skin in young women, with no adverse effects reported.

This review highlights the challenges in screening for steroid 5 alpha-reductase inhibitors and discusses significant variability in the effectiveness of finasteride and dutasteride, calling for standardized testing methods to develop safer, more specific inhibitors from herbal preparations.

This review discusses management strategies for androgenic alopecia using plant derivatives and highlights the need for prolonged efficacy but reports no new clinical findings.

This study found that coconut oil with turmeric is less effective than 2% ketoconazole shampoo at reducing itching, hair loss, and dandruff scales in adults with dandruff.

This review discusses the potential of Lansium domesticum as a herbal medicine, summarizing its traditional uses, nutritional value, bioactivities, and related nanoparticles and pharmaceutical formulations, but reports no new experimental results.

This study found that 3% peppermint oil significantly enhanced hair growth in C57BL/6 mice, showing increased dermal thickness, follicle number, and follicle depth compared to other treatments.

This study found that Cacumen Platycladi volatile oil promotes dermal papilla cell proliferation and enhances hair growth in mice, outperforming minoxidil and showing no obvious cytotoxic effects.

This review identified 12 herbal plants producing essential oils with pharmacological activities that stimulate hair growth, potentially through enhanced scalp microcirculation, inhibition of 5α-reductase, anti-inflammatory and antioxidant effects, anagen phase stimulation, and increased dermal papilla cell proliferation.

In this study, the authors reviewed various herbal ingredients used in hair care products and found that components like aloe vera, hibiscus, amla, and fenugreek have traditional and scientifically validated benefits for addressing hair issues such as hair loss, dandruff, and damage.

This review evaluates the literature on the ethnopharmacology, phytochemistry, and therapeutic potential of Darmana Turki (Artemisia maritima L.) and reports no new clinical findings.

This review discusses side effects and allergy contact dermatitis caused by essential oils in cosmetic products and reports no new clinical results.

This review discusses the potential benefits of using natural permeation enhancers to improve transdermal drug penetration in formulations like emulgel, a promising topical delivery system for hydrophobic drugs.