32 citations,
July 2017 in “Wiley Interdisciplinary Reviews-Developmental Biology” Transit-amplifying cells are crucial for tissue repair and can contribute to cancer when they malfunction.
26 citations,
June 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Regenerative therapies show promise for treating vitiligo and alopecia areata.
23 citations,
January 2021 in “Scientific Reports” Adding human blood vessel cells to hair follicle germs may improve hair growth and quality.
22 citations,
November 2012 in “Journal of cosmetic dermatology” Stem cells can rejuvenate skin, restore hair, and aid in wound healing.
3 citations,
January 2012 in “Elsevier eBooks” Burn scars form abnormally due to changes in wound healing, and more research is needed to improve treatments.
January 2020 in “Asian journal of applied science and technology” Good nutrition is crucial for health and preventing disease, and supplements can help prevent nutrient deficiencies.
2 citations,
May 2006 in “Women's Health Medicine” Ovulation disorders are a major cause of infertility and menstrual problems in women.
77 citations,
March 2014 in “Cold Spring Harbor Perspectives in Medicine” Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
49 citations,
March 2019 in “Journal of Investigative Dermatology” Skin fat plays a key role in immune defense and healing beyond just storing energy.
42 citations,
February 2021 in “Signal Transduction and Targeted Therapy” Hair follicle regeneration possible, more research needed.
1 citations,
January 2023 in “Science Advances” The skin's microbiome helps hair regrow by boosting certain cell signals and metabolism.
25 citations,
September 2018 in “Molecular Biology of the Cell” Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.
22 citations,
July 2015 in “PloS one” Foxp1 helps control hair stem cell growth and response to stress during hair growth cycles.
12 citations,
June 2020 in “Frontiers in Cell and Developmental Biology” The PP2A-B55α protein is essential for brain and skin development in embryos.
11 citations,
August 2021 in “Aging” Collagen and TGF-β2 help maintain hair cell shape and youthfulness.
Certain natural products may help stimulate hair growth by affecting stem cell activity in the scalp.
1 citations,
May 2023 in “European Journal of Human Genetics” Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.
51 citations,
August 2013 in “The Journal of experimental medicine/The journal of experimental medicine” Loss of a specific protein in skin cells causes symptoms similar to psoriasis.
Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.
222 citations,
August 2009 in “Experimental Dermatology” Stem cells are crucial for wound healing and understanding their role could lead to new treatments, but more research is needed to answer unresolved questions.
4 citations,
July 2022 in “Frontiers in Cell and Developmental Biology” The document concludes that understanding adult stem cells and their environments can help improve skin regeneration in the future.
October 2023 in “Biomaterials” Nanotechnology could improve hair regrowth but faces challenges like complexity and safety concerns.
November 2022 in “Regenerative Therapy” Advancements in tissue engineering show promise for hair follicle regeneration to treat hair loss.
508 citations,
February 2007 in “Cell” Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.
488 citations,
July 2021 in “Cell” Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.
31 citations,
April 2019 in “Cell reports” Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.
5 citations,
December 2021 in “Frontiers in Cell and Developmental Biology” Enzymes called PADIs play a key role in hair growth and loss.
2 citations,
September 2022 in “Frontiers in Immunology” T-regulatory cells are important for skin health and can affect hair growth and reduce skin inflammation.
13 citations,
September 2017 in “Oncotarget” A certain signaling pathway in mice, when increased, causes hair to gray by depleting the cells that give hair its color.
33 citations,
January 2018 in “Blood” Ruxolitinib helps protect skin stem cells and keeps skin healthy in mice with skin GVHD.