June 2023 in “NILES Journal forGeriatric and Gerontology/NILES Journal for Geriatric and Gerontology” In this study, oral tranexamic acid significantly improved melasma in 40 female patients over three months, with no adverse effects like post-inflammatory hyperpigmentation or bleeding, demonstrating its potential as a safe and effective treatment option.
12 citations
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January 2013 in “Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz” Older adults still engage in sexual activities but face challenges like health issues and lack of professional support, highlighting the need for better healthcare provider education and research on sexual fulfillment in old age.
5 citations
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August 2018 in “Urology” This study found that independent pharmacies in the St. Louis area offer significantly lower prices for tamsulosin and oxybutynin ER compared to chain pharmacies, while zip-code and median income show no pricing correlation.
34 citations
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December 2012 in “Current Opinion in Clinical Nutrition and Metabolic Care” This review discusses the potential of DHEAS and testosterone treatments to increase muscle mass in older men with sarcopenia, while effects on muscle function and physical performance remain unclear, and calls for further research on optimized approaches.
19 citations
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April 2015 in “Stem Cells” This study demonstrated that supplementing aged mice with pro-IGF-II improved muscle regeneration by enhancing satellite cell proliferation and reducing adipogenesis, suggesting potential benefits for treating muscle injuries in elderly individuals.
4 citations
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November 2023 in “Frontiers in immunology” In this narrative review, researchers outlined the role of T cells in the autoimmune pathogenesis of alopecia areata and highlighted ongoing research into therapeutic pathways, beyond current JAK inhibitors, aimed at developing new treatments for the disease.
March 2008 in “Aging health” This research reported that docetaxel is generally safe and effective for elderly patients with solid tumor malignancies, showing no significant age-related differences in efficacy or toxicity.
27 citations
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July 2015 in “International Journal of Dermatology” This study found that skin disorders are prevalent among elderly individuals and are often associated with underlying systemic diseases.
24 citations
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January 2012 in “Journal of Cellular Biochemistry” This study found that C-reactive protein may enhance monocyte adhesion to endothelial cells through NOX-mediated oxidative stress, suggesting a potential mechanism for atherogenesis.
21 citations
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February 2016 in “Reproductive Biomedicine Online” This review examines how genetic variants associated with polycystic ovary syndrome affect reproductive success differently in men and women, supporting the theory that intralocus sexual conflict may explain its persistence.
19 citations
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August 2020 in “Gastroenterology report” This review discusses the characteristics and challenges in treating Cronkhite–Canada syndrome but reports no new clinical findings, emphasizing the need for better understanding and uniform treatment approaches.
15 citations
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January 2018 in “Biomedical Reports” This review discusses multiple pathways through which exosomes may regulate skin functions and diseases like melanoma, scleroderma, and pigmentation disorders, without providing new clinical results; future therapeutic strategies are suggested.
6 citations
,
March 2016 in “British Journal of Dermatology” This study reports that low levels of HDL cholesterol and IGF-1 were associated with a higher risk of hair loss in middle-aged women, but causal relationships remain uncertain.
3 citations
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May 2018 in “Biochemical and Biophysical Research Communications” In this study, researchers found that inhibiting inducible nitric oxide synthase (iNOS) promoted hair growth in diabetic mice, suggesting iNOS-derived nitric oxide contributes to hair loss under diabetic inflammatory conditions.
3 citations
,
January 2018 in “Postępy Dermatologii i Alergologii” This study suggests that SRD5A2 polymorphisms may increase the risk of acne in individuals with normal serum testosterone levels, particularly in the Chinese population.
1 citations
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April 2009 in “Cochrane Database of Systematic Reviews” This protocol outlines a planned Cochrane Review assessing the effectiveness and safety of treatments for androgenic alopecia in women, reporting no new research findings.
1 citations
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January 2009 in “Cochrane Database of Systematic Reviews” This protocol outlines a planned Cochrane Review to evaluate the effectiveness and safety of treatment options for androgenic alopecia in women, without reporting new findings yet.
This study suggests that topical application of a hydrogel containing magnetized saline water may promote wound healing in stage 2-3 pressure ulcers in elderly patients by stimulating autophagy, based on observed clinical improvements in a case series.
December 2023 in “Y Dược học” In this study, researchers found that 11.5% of older outpatients in Vietnam experienced post-COVID-19 hair loss; women, those single or divorced, and individuals with prior COVID-19 hospitalizations were more likely to report hair loss.
October 2023 in “Journal of Medicine, University of Santo Tomas (JMUST Online)” This study reported that among Filipino elderly patients, xerosis/xerotic eczema was the most common dermatological condition leading to consultation, with inflammatory dermatoses being the predominant category of skin diseases observed from 2014 to 2018 at a tertiary hospital's dermatology service.
This article reviews the nutritional needs and challenges for the elderly, emphasizing the benefits of antioxidants and healthy fats for immune support and overall health, but presents no new clinical results.
195 citations
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February 2007 in “The Journal of Clinical Endocrinology and Metabolism” In this study, administering 5alpha-reductase inhibitors reduced dihydrotestosterone levels and was associated with mild, reversible decreases in semen parameters in healthy men.
104 citations
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March 2014 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” In this study, DHT and calculated free DHT were linked to higher risks of incident cardiovascular disease and all-cause mortality in elderly men, while total testosterone and calculated free testosterone showed no such associations.
72 citations
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April 2008 in “The Journal of urology/The journal of urology” This study found that 1-year use of 5alpha-reductase inhibitors, dutasteride or finasteride, significantly lowered dihydrotestosterone levels without adversely affecting bone density, lipids, or hemoglobin in normal men.
38 citations
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December 2011 in “Journal of Dermatology” This article reviews current guidelines for managing androgenetic alopecia and highlights the need for guidelines tailored to Japan; it reports no new clinical results.
26 citations
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August 2014 in “PubMed” This study found that testosterone treatment in older hypogonadal men caused minor improvements in depressive symptoms and visuospatial memory, but overall, major cognitive benefits were not observed.
14 citations
,
January 2020 in “International Journal of Biological Sciences” This study found that ranitidine and finasteride may have cardiovascular and renal protective effects in mice by inhibiting TMAO synthesis and improving gut microbiota composition.
11 citations
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December 2010 in “The Journal of Urology” This study found that combining oral testosterone with dutasteride increased testosterone bioavailability in hypogonadal men while suppressing dihydrotestosterone levels over a 28-day period.
10 citations
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November 2022 in “Protein & Cell” In this study, topical quercetin was found to stimulate hair follicle growth and promote microvascular regrowth in mice, suggesting its potential for hair regrowth strategies.
10 citations
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June 2001 in “Annals of neurology” This study reports that patients with Alzheimer's disease have increased levels of polyamines in their hair.