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Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.

After menopause, women lose a lot of skin collagen, but estrogen replacement might improve skin health.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.

Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.

Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

Finasteride may cause floppy-iris syndrome during cataract surgery, so check patients' medical history.

The document concludes that more research is needed to understand how to treat muscle pain with drugs.

The vitamin D receptor is essential for skin stem cells to grow, move, and become different cell types needed for skin healing.

Silicon can improve skin and hair health, but more research is needed.

Menopause significantly reduces skin collagen, leading to thinner, less elastic skin, and hormone replacement may help but requires careful consideration.

Some people experience severe, long-lasting side effects from fluoroquinolone antibiotics, leading to the recommendation of limited use and increased awareness of these risks.

Using steroids can increase the risk of heart problems.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The current system can't fully test all combination treatments, so alternative methods and regulatory flexibility are needed.

Men's hair loss is caused by hormones and genes, and can be treated with medication and surgery, while graying is due to aging and has no prevention except dyeing.

Bariatric surgery may help severely obese teenagers but has risks and requires careful patient selection and long-term care.

Different drugs for prostate-related urinary symptoms work but have various side effects, and treatment should be tailored to the individual.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.

Finasteride doesn't affect bone density in male rats.

Corticosteroids may effectively regrow hair in Alopecia Totalis with manageable side effects.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

Ozone therapy might improve cancer treatment and reduce its side effects.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.

St. John's Wort extract and oil safety in cosmetics is unclear; more data needed on photosensitization, toxicity, and human irritation.