April 2023 in “Journal of Investigative Dermatology” This study found that the type 2 cytokines IL-4 and IL-13 may amplify Staphylococcus aureus-induced inflammation and barrier disruption in atopic dermatitis, potentially worsening skin defense against this bacterium.
This study found that inhibiting AP-1 transcription factors in mice causes squamous tumors to transform into sebaceous tumors and regulates tumor cell lineage.
This study found that inhibiting AP-1 activity in mice can induce lineage transdifferentiation between squamous and sebaceous tumors, suggesting AP-1's role in maintaining tumor cell identity.
January 2009 in “Springer eBooks”
8 citations
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February 2016 in “The American Journal of Dermatopathology” In this study, the researchers found that transplanted hair follicles undergo significant morphological changes, including a thickened dermal sheath and increased hair shaft diameter, which are associated with altered follicular vascularization.
7 citations
,
October 2000 in “Allergo Journal” Stress may affect hair growth by influencing hair follicle development and could contribute to hair loss.
4 citations
,
January 2015 in “International Journal of Trichology” In this study, transplanted hair follicles from different body sites showed changes in morphology and immune status, suggesting their ability to adapt and function in new recipient areas such as the scalp or eyebrows.
208 citations
,
January 2013 in “Lab on a Chip” The researchers described a chip-based bioreactor platform for dynamic perfusion, which may enhance in vitro skin models by introducing mechanical shear stress and extending culture periods.
29 citations
,
April 2020 in “Journal of Tissue Engineering and Regenerative Medicine” This study demonstrates that incorporating human neopapilla into reconstructed human skin can initiate hair follicle morphogenesis by stimulating epidermal invagination and maintaining follicle-inductive properties in vitro.
4 citations
,
December 2023 in “Research Review” In this retrospective cohort study, researchers reported that 77% of 300 COVID-19 survivors experienced long COVID-19 symptoms such as fatigue and hair loss, with symptoms more likely in females, younger age groups, and hospitalized patients.
14 citations
,
May 2013 in “Emerging infectious diseases” This case study reports a prolonged incubation period of over 8 years for a C. gattii infection in a cat that likely originated from exposure in California, suggesting the fungus may remain dormant longer than previously thought.
1 citations
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March 1997 in “Journal of the American Pharmaceutical Association” This guideline summary, endorsed by six Spanish pediatric societies, outlines consensus recommendations for managing childhood asthma, emphasizing diagnosis, maintenance treatment with low-dose inhaled corticosteroids, and patient education for effective control.
January 2025 in “Medical Research Archives” In this review, researchers reported that anorexia nervosa leads to widespread medical complications across all body systems, particularly at low body weights, and these complications are primarily treated through nutritional rehabilitation with a multidisciplinary team approach.
June 2021 in “Current Research in Diabetes & Obesity Journal” This study discusses experiences with managing postoperative complications after bariatric surgery, such as psychological disorders, hair loss, nutritional deficiencies, and other issues, highlighting the need for effective interventions to prevent comorbidities while acknowledging the procedure's generally low complication rates.
June 2019 in “Poster presentations” This study found that low dose methotrexate did not increase hair loss in rheumatoid arthritis patients compared to healthy controls, and many patients even showed a reduction in hair fall over the short term.
October 2017 in “Journal of medical science and clinical research” This study found that obese individuals commonly experienced skin manifestations such as acanthosis nigricans, hyperandrogenism features, and increased cutaneous infections compared to non-obese individuals.
November 2013 in “Annales de Dermatologie et de Vénéréologie” This study found that extracts of Punica granatum L. improved hair growth and demonstrated significant anti-lice and antidandruff activity in a mouse model.
658 citations
,
June 2003 in “Endocrine reviews” This review discusses the role of androgens in the progression of cardiovascular disease and explores novel therapeutic targets without reporting new clinical results.
506 citations
,
January 2012 in “Molecular and Cellular Endocrinology” This review details the expression and diverse functions of melatonin receptors in non-neural tissues and reports no new clinical findings, emphasizing their potential as therapeutic targets across various physiological and pathological processes.
316 citations
,
June 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that using a standardized protocol with microspheres of approximately 1.5 micrometers enhances penetration into hair follicles, particularly when skin is treated with cyanoacrylate skin surface stripping.
252 citations
,
February 2018 in “npj Regenerative Medicine” This review explores recent advances in understanding molecular mechanisms of tissue regeneration in mammals and suggests potential therapeutic targets, but it reports no new clinical results.
222 citations
,
January 2005 in “Endocrine journal” This article discusses the potential role of melatonin in protecting skin against stress and maintaining homeostasis, based on its local synthesis and various protective functions, but presents no new clinical results.
182 citations
,
August 2016 in “Development” This review discusses the roles and mechanisms of chromatin remodelers and their subunits in mammalian development, but reports no new experimental results.
157 citations
,
August 2010 in “Lupus” This review discusses the various common, rare, and unusual skin manifestations of lupus erythematosus and highlights the importance of accurate diagnosis, but it reports no new clinical results.
150 citations
,
February 2013 in “Surgical Infections” This review discusses the historical and modern use of silver for reducing infections and aiding healing in burns, wounds, and medical devices, noting its benefits and limitations in various applications.
144 citations
,
August 2019 in “Cells” This review discusses the WNT signaling pathway's involvement in human diseases and highlights recent advances in WNT-related treatments, but it presents no new research findings.
131 citations
,
January 2018 in “Scientific Reports” In this study, mycorrhizal fungal inoculation was associated with increased root-hair growth and enhanced drought tolerance in trifoliate orange by modulating auxin synthesis and transport under water stress conditions.
125 citations
,
September 2001 in “The FASEB Journal” This study demonstrated that stress inhibited hair growth in mice, likely through substance P-dependent activation of immune cells, highlighting a brain-hair follicle connection.
116 citations
,
February 2017 in “Journal of the American Academy of Dermatology” This systematic review found that Janus kinase inhibitors have shown beneficial effects for psoriasis and alopecia areata, with promising preliminary results in other skin conditions, though more research is needed to define dosing and safety profiles.
108 citations
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July 2002 in “Molecular and cellular biology” This study found that overexpressing Dsg3 in the suprabasal epidermis of transgenic mice resulted in flaking skin and abnormal hair growth, supporting Dsg3's role in regulating epidermal differentiation.