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Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

The document concludes that managing skin conditions during pregnancy is important and requires specialized care.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.

Boreal caribou in northeastern British Columbia have significant health issues, including infections, tick infestations, and mineral deficiencies.

Albumin and prednisone improved symptoms in a woman with Cronkhite-Canada syndrome, revealing potential genetic causes.

Geriatric Julia Creek dunnarts often suffer from reproductive and skin diseases, impacting conservation efforts.

Environmental factors and chemicals might affect hormone balance and contribute to common hair loss.

A new gene variant causes glucocorticoid resistance in a mother and son.

Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.

With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.

Women with congenital adrenal hyperplasia have lower fertility, but with proper treatment, they can conceive successfully.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

People with alopecia areata have more Th17 cells and fewer Treg cells, which may be key to the condition's development.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

People with Major Depressive Disorder have a higher chance of getting Alopecia Areata, and vice versa; antidepressants may lower this risk.

Hydroxychloroquine showed some potential, but overall, the three drugs had limited success in treating lupus in dogs.

Post-finasteride patients show changes in gut bacteria, possibly causing various symptoms.

Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.

Collecting hair for cortisol analysis is possible in low-income mother-toddler pairs.

Finasteride may affect PNMT, causing side effects.

Longer TA repeats in the SRD5A2 gene may increase acne risk in Chinese people.

The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."

Alopecia areata is caused by immune system attacks on hair follicles, often triggered by viral infections.

Altering maternal cortisol during pregnancy can improve wool growth in Merino sheep.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.