Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study examined noninvasive tissue samples, including buccal swabs, hair follicles, saliva, and urine cell pellets, and found hair follicles and urine cell pellets promising for transcriptomic and clinical analyses due to their sample quality and performance in disease-relevant applications.

Light skin shows more inflammation from sun exposure than dark skin.

This study identified 24 independent genetic variations and 127 unique genes associated with nociplastic pain, suggesting it is a complex, heritable trait with links to various cognitive and metabolic pathways.

This study found that individuals with androgenetic alopecia had higher scalp microbiome diversity and more complex scalp-gut microbiome networks than those without, suggesting a link between skin-gut microorganisms and hair loss development.

This study identified key genes and pathways related to wool follicle development in coarse wool lambs, suggesting epigenetic factors may influence wool sheep domestication and breeding.

In this study, researchers found that significant transcriptomic changes occur in the skin of Dezhou donkey foals as they age from newborns to one year old, involving gene expression shifts that may enhance skin barrier function and hair follicle development, while reducing collagen synthesis.

This study observed a microbial shift on the scalp of Alopecia areata patients, characterized by an increase in Propionibacterium acnes and a decrease in Staphylococcus epidermidis, compared to healthy controls.

This article emphasizes the need for dermatology to treat gender identity, gender, and sex as distinct factors, aiming to improve patient-specific risk assessment and treatment alignment, and highlights a research gap in distinguishing sex and gender as separate risk factors in the field.

This study identified genetic loci and pathways associated with long hair growth in the Tianzhu white yak, providing new insights into the genetic mechanisms of this trait.

This study demonstrates a varied distribution of keratins in the epidermis of the Malayan pangolin, suggesting evolutionary adaptations related to their distinctive scales.

This study found that variations in the IL16 gene, specifically SNPs rs17875491 and rs11073001, may be associated with increased risk and phenotype expression of alopecia areata in the Korean population.

This study observed that colorectal cancer tumoroids adapted to an environment without a matrix by developing disordered self-assembly, but their tumor-specific phenotypes and drug sensitivity remained unchanged.

This study found that intron 3 VNTR polymorphism in the IL-4 gene may be associated with an increased risk of alopecia areata in the Turkish population.

This study found that the gene BSSP, a serine protease, is predominantly expressed in sebaceous glands and is overexpressed in nude mouse skin.

This study identified three new genetic loci associated with PCOS and found a similar genetic structure across different diagnostic criteria, suggesting a genetic basis for shared metabolic traits and potential causal links to other conditions.

In this study, researchers performed a genome-wide characterization of the Wnt gene family in domestic donkeys, identifying 19 genes and highlighting their evolutionary conservation among mammals, along with tissue-specific expression patterns potentially linked to reproductive regulation and tissue homeostasis.

This article reviews the cellular and molecular processes of acute and chronic wound healing, emphasizing the need for collaboration between researchers and clinicians to advance therapeutic solutions; it presents no new clinical results.

This study reported the discovery of large-scale haplotypes (cenhaps) in human centromere regions, revealing deep genetic diversity, including introgressed Neanderthal and ancient African lineages.

This study found that the genetic variants rs231775 and rs3087243 of the CTLA4 gene are not associated with alopecia areata in the Mexican population analyzed.

This review highlights recent advances in ultrasound-based radiomics and radiogenomics for ovarian cancer, suggesting these techniques improve diagnostic accuracy and patient-specific treatment strategies, despite ongoing challenges with standardization and model interpretability.

This study found that neonatal blocking of androgen and estrogen pathways in rats altered sex-specific expression of estrogen and androgen receptors in adult pituitary and adrenal glands, potentially influencing lifelong neuroendocrine function.

In this study, fibroblasts from long-term skin biopsy cultures retained their ability to reprogram into induced pluripotent stem cells after 16 months, despite undergoing transcriptional changes and decreased proliferation rates over successive generations.

This study found that the superior growth and higher zinc uptake of wild-type barley compared to its root-hairless mutant in zinc-deficient soil is mainly due to greater root surface area from root hairs.

This study identified three variants in the HR gene among Mexican patients with alopecia areata, with one novel variant potentially serving as a risk factor for the disease.

Dark skin has stronger barriers and structure due to specific gene activity.

Estrogen may help improve COVID-19 outcomes, especially in women.

This study identified at least four distinct fibroblast populations in adult human skin, each with unique functional properties, suggesting potential therapeutic applications for wound healing and fibrosis-related diseases.

This study found that both genome-wide screening methods identified the VTRNA2-1 epiallele as highly responsive to environmental influences, suggesting a link between early embryonic environment, epigenetic changes, and human disease.

This study found that nuclear androgen receptors are not necessary for androgen self-administration, suggesting that plasma membrane receptors might be involved.

This study found that in Chinese goat breeds, specific genetic variations, particularly in Tibetan Cashmere goats, are associated with traits like hair growth and adaptation to high-altitude environments.