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The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Fat cells help recruit healing cells and build skin structure during wound healing.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

Understanding where cancer cells come from helps create better prevention and treatment methods.

Diet changes can protect against harmful environmental effects on fetal development.

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

The Rotterdam Study aims to understand various diseases in older adults.

Guidelines suggest various treatments for alopecia areata, but leaving it untreated is also an option as 80% cases may recover on their own.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.

Different types of skin cells play specific roles in development, healing, and cancer.

Androgens can both increase and decrease hair growth in different parts of the body.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

WNT10A mutations often cause ectodermal dysplasias, with males showing more tooth issues than females.

Ruxolitinib effectively regrows hair in most patients with severe hair loss.

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

Fungi-produced compounds can change plant root growth.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.