July 2021 in “Advances in laboratory medicine” This article reviews differential diagnosis approaches for 46,XY DSD, proposing a diagnostic algorithm focused on biochemical and genetic data, without presenting new clinical results.
June 2020 in “International Journal of Research in Dermatology” This study assessed clinical patterns of skin and mucosal symptoms in postmenopausal women, finding that a significant number experienced conditions like atrophic vaginitis, oral complaints, and hair loss, often without realizing their menopausal link.
March 2019 in “Nasza Dermatologia Online” A man had both alopecia areata and lichen planus, which is uncommon.
January 2018 in “Elsevier eBooks” This review discusses the role of DHT in male sexual differentiation and fertility in individuals with 5α-reductase-2 deficiency, reporting no new clinical results.
September 2017 in “Journal of Investigative Dermatology Symposium Proceedings” This report highlights four cases where squamous cell carcinoma was misdiagnosed in individuals with darker skin, emphasizing the challenges in accurate diagnosis for this population.
September 2017 in “Clinical and Experimental Dermatology” The document summarized various dermatology studies and case reports.
March 2016 in “The Journal of Urology” This historical review traces the discovery of 5-alpha reductase inhibitors, widely used in urology, from the study of guevedoces, Dominican children with a rare disorder leading to significant androgenization at puberty.
February 2013 in “Journal of The American Academy of Dermatology” Oral propranolol successfully treated a baby's skin growth and ulceration linked to PELVIS syndrome.
November 2012 in “Experimental and Clinical Endocrinology & Diabetes” This case report describes a 46,XY female patient with a novel homozygous nonsense mutation in the LHCGR gene, highlighting the need for molecular analysis in disorders of sexual development.
September 2006 in “Pediatrics in Review” This case report highlights a 16-year-old girl with primary amenorrhea diagnosed with complete androgen insensitivity syndrome after chromosomal analysis revealed a 46,XY karyotype.
September 1998 in “Journal of The European Academy of Dermatology and Venereology” Aging affects hair density and skin health, and Behcet's disease, a complex condition with no specific test, involves sores and systemic issues, treated with various medications.
237 citations
,
January 2010 in “The Journal of Sexual Medicine” The authors updated recommendations on diagnosing and treating women's sexual dysfunctions, emphasizing a comprehensive assessment approach, while noting the need for further multidisciplinary research.
100 citations
,
May 2011 in “Journal of Pediatric and Adolescent Gynecology” This review covers the pathophysiology, diagnosis, and treatment of congenital adrenal hyperplasia due to 21-hydroxylase deficiency and reports no new findings.
28 citations
,
January 2012 in “Case Reports in Medicine” This article discusses Hair-thread Tourniquet Syndrome in children, emphasizing the need for prompt examination and intervention to prevent severe complications, but reports no new clinical results.
20 citations
,
July 2015 in “Journal der Deutschen Dermatologischen Gesellschaft” This review summarizes the anticarcinogenic, anti-inflammatory, and other health effects of green tea, noting its historical and ongoing use in dermatological and cosmeceutical applications, but reports no new clinical results.
7 citations
,
January 2012 in “International Journal of Trichology” A man with Woolly Hair Syndrome had very curly, fragile hair, and doctors used a special scalp examination to diagnose him without invasive tests.
3 citations
,
November 2021 in “IntechOpen eBooks” This chapter reviews the role of the testes in producing and functioning of testicular androgens and protein hormones, but it presents no new clinical results.
1 citations
,
December 2015 in “International journal of pediatric research” This review discusses the occurrence of hair tourniquets in children and adolescents, reporting no new clinical results but highlighting case variations by age and affected body part.
January 2026 in “Vestnik dermatologii i venerologii” In this review, the authors report that tacrolimus ointment shows promise for expanding its use to a variety of skin conditions, beyond its current approval for atopic dermatitis, by analyzing clinical experiences of its application for rosacea, seborrheic dermatitis, psoriasis, and other dermatoses.
August 2022 in “Dermatological Reviews” This study highlighted significant recent advancements in vitiligo transplantation surgery, improving graft orientation, donor-to-recipient ratios, and ease of technique in hair follicle transplants, alongside enhanced site preparation methods and improved procedural success rates.
February 2010 in “ePrints Soton (University of Southampton)” This research found that androgen bioactivity plays a role in normal female sexual differentiation, suggesting females develop within a significant androgenic environment, with implications for understanding conditions like congenital adrenal hyperplasia.
November 2022 in “International Journal of Trichology” This case study reports a 25-year-old male developing an extensive psoriasiform eruption within a week after starting finasteride 1 mg for androgenetic alopecia.
482 citations
,
June 1979 in “Proceedings of the National Academy of Sciences” This study demonstrated that keratin is widely present in various epithelial cells, providing structural strength and potential insights into the origin of cell lines.
309 citations
,
June 2001 in “Molecular and Cellular Endocrinology” Mutations in the androgen receptor gene cause androgen insensitivity, leading to female traits in genetically male individuals.
218 citations
,
December 2011 in “Advances in Urology” This review discusses the biochemical properties and clinical significance of 5 alpha-reductase isozymes and reports no new clinical results.
165 citations
,
January 2014 in “Dermatology Research and Practice” This review discusses the various dermatological applications of zinc, including its use in treating infections, inflammatory dermatoses, pigmentary disorders, and neoplasias, and reports no new clinical findings.
155 citations
,
June 2009 in “International Journal of Dermatology” This extensive review discusses the clinical manifestations, potential associations, and treatment approaches for lichen planus, but reports no new clinical results, highlighting gaps in evidence for therapeutic strategies.
131 citations
,
March 2004 in “The American journal of pathology” This study found that modulating BMP activity in transgenic mice affects the development and characteristics of several ectodermal organs, such as skin, hair, and claws, highlighting a stage-dependent influence on organogenesis.
101 citations
,
April 1994 in “Baillière's clinical endocrinology and metabolism” This review discusses the role of 5α-reductase enzymes in androgen action and related disorders, noting that their specific inhibitory drugs show promise for conditions like benign prostatic hypertrophy; it reports no new clinical results.
96 citations
,
September 1975 in “The Journal of Clinical Endocrinology & Metabolism” In this study, significant elevations of DHA and testosterone were associated with pubic hair development and voice changes in boys during puberty.