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Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

Researchers created a cell line to study hair growth and found specific genes affected by dihydrotestosterone.

Testosterone may slow down wound healing and increase inflammation.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.

Cells from balding scalps have more androgen receptors than cells from non-balding scalps.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Too much androgen can cause hair loss; finasteride may help.

Finasteride effectively treats baldness but may cause sexual side effects.

New compounds called benzoquinolinones may treat conditions linked to excess DHT.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

Different women's hair and skin glands respond to hormones in varied ways, which can cause unwanted hair growth even with normal hormone levels, and more research is needed to treat this effectively.

DHT, a testosterone byproduct, causes male pattern baldness.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.