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Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Cells from balding scalps have more androgen receptors than cells from non-balding scalps.

Knowing about finasteride's sexual side effects increases reported dysfunction.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Finasteride effectively treats BPH, but needs more trials to understand potential.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Sebocytes play a key role in controlling androgen levels in human skin.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

Toxic Shock Syndrome mainly affects menstruating women, can recur, and is linked to staph bacteria, with rapid treatment being crucial.

Some medicinal plants can help heal wounds and may lead to new treatments.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

High androgen levels in young women with PCOS are linked to higher blood pressure.

Zinc is effective for treating various skin conditions, including warts and acne.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

New insights show Lichen Planopilaris is a rare, scarring hair loss condition, hard to treat, mainly affecting middle-aged women, and significantly impacts mental health.

Zinc is crucial for growth and health in rats.