Search
for

    Sort by

    Research

    180-210 / 1000+ results
      Hoxc13 Mutant Mice Lack External Hair

      research Hoxc13 mutant mice lack external hair

      245 citations , January 1998 in “Genes & Development”
      This study found that Hoxc13 mutations in mice cause defects in hair, nail, and tongue structures, with the most noticeable issue being brittle hair leading to alopecia.
      Cutaneous Adverse Effects of Targeted Therapies

      research Cutaneous adverse effects of targeted therapies

      192 citations , January 2015 in “Journal of the American Academy of Dermatology”
      This review discusses skin-related toxicities associated with targeted cancer therapies and emphasizes the need for dermatologists to understand and manage these adverse effects, but reports no new experimental results.
      Inhibitors of 5α-Reductase in the Treatment of Benign Prostatic Hyperplasia

      research Inhibitors of 5α-Reductase in the Treatment of Benign Prostatic Hyperplasia

      52 citations , February 2006 in “Current pharmaceutical design”
      This review discusses the use of 5α-reductase inhibitors in treating benign prostatic hyperplasia, highlighting their long-term effectiveness and benefits when combined with α1-adrenergic antagonists; it reports no new clinical results.
      Novel Inhibitors of 5α-Reductase

      research Novel inhibitors of 5α-reductase

      20 citations , February 2002 in “Expert Opinion on Therapeutic Patents”
      This review discusses the potential uses of 5α-reductase inhibitors for conditions ranging from benign prostatic hyperplasia to skin disorders like acne and male pattern baldness, but it reports no new clinical results.
      Discovery of Natural Steroid 5 Alpha-Reductase Inhibitors

      research Discovery of Natural Steroid 5 Alpha-Reductase Inhibitors

      11 citations , December 2018 in “Assay and Drug Development Technologies”
      This review highlights the challenges in screening for steroid 5 alpha-reductase inhibitors and discusses significant variability in the effectiveness of finasteride and dutasteride, calling for standardized testing methods to develop safer, more specific inhibitors from herbal preparations.

      research Telocytes of the male reproductive system: dynamic tissue organizers

      8 citations , October 2024 in “Frontiers in Cell and Developmental Biology”
      This review suggests that telocytes in male reproductive organs help organize tissue structure and paracrine factors, impacting organ development and pathology, but more research is needed on their molecular pathways.
      The Acne Hormones

      research The acne hormones

      November 2014 in “John Wiley & Sons, Ltd eBooks”
      This review discusses hormones that affect acne and highlights a statistically significant link between a low-glycemic-load diet and reduced acne activity, but reports no new experimental findings.
      Combined Oral Contraceptives Promote Androgen Receptor And Estrogen Receptor Alpha Upregulation In The Female Prostate (Skene’s Paraurethral Glands) Of Adult Gerbils (Meriones Unguiculatus)

      research Combined oral contraceptives promote androgen receptor and oestrogen receptor alpha upregulation in the female prostate (Skene’s paraurethral glands) of adult gerbils (Meriones unguiculatus)

      3 citations , January 2018 in “Reproduction, Fertility and Development”
      This study concluded that cyproterone acetate alone produced antiandrogenic effects on the female gerbil prostate, while ethinyloestradiol alone stimulated estrogenic activity, and their combination led to prostatic lesions.
      Hormonal Therapy for Acne

      research Hormonal Therapy for Acne

      1 citations , November 1996 in “Journal of Cutaneous Medicine and Surgery”
      Hormones, especially androgens, play a key role in causing acne, and treatments like hormone control pills and hormone-blocking medications can help.
      Testosterone: The Male Sex Hormone

      research Testosterone: The Male Sex Hormone

      May 2023 in “IntechOpen eBooks”
      This review outlines the role of testosterone in male sexual development and its therapeutic use for male hypogonadism, covering its biosynthesis, secretion, metabolism, and various biological actions, but does not report specific study results.
      An Unusual Cause of Primary Amenorrhea

      research An Unusual Cause of Primary Amenorrhea

      May 2021 in “Journal of the Endocrine Society”
      In this case report, an 18-year-old Vietnamese female with primary amenorrhea and normal female phenotype was most likely diagnosed with müllerian agenesis, highlighting its association with embryologic underdevelopment of the müllerian duct.
      Role of 5α-Reductase in Health and Disease

      research 9 Role of 5α-reductase in health and disease

      101 citations , April 1994 in “Baillière's clinical endocrinology and metabolism”
      This review discusses the role of 5α-reductase enzymes in androgen action and related disorders, noting that their specific inhibitory drugs show promise for conditions like benign prostatic hypertrophy; it reports no new clinical results.

      research Physiology of Testicular Function

      4 citations , January 2023 in “Andrology”
      This review discusses the structure and function of the testes in male reproduction and development, noting the complex hormonal regulation within the hypothalamic-pituitary-gonadal axis but reports no new clinical results.
      Obstetric and Gynecologic Dermatology

      research Obstetric and Gynecologic Dermatology

      May 2002 in “British Journal of Dermatology”
      A pregnant woman's skin condition improved after giving birth, possibly due to high estrogen levels during pregnancy.
      Epithelial Stem Cells: Turning Over New Leaves

      research Epithelial Stem Cells: Turning over New Leaves

      508 citations , February 2007 in “Cell”
      This article reviews the biology of epithelial stem cells and their role in tissue self-renewal, maintenance, and regeneration, and it highlights the clinical implications of understanding their signaling pathways, but it presents no new clinical findings.
      Current Evaluation of Amenorrhea

      research Current evaluation of amenorrhea

      78 citations , November 2008 in “Fertility and Sterility”
      Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

      research Steroid Sulfatase in the Human Hair Follicle Concentrates in the Dermal Papilla

      61 citations , December 2001 in “Journal of Investigative Dermatology”
      This study found that steroid sulfatase in the dermal papilla of hair follicles metabolizes dehydroepiandrosterone sulfate to support the development of androgenetic alopecia, suggesting potential for steroid sulfatase inhibitors as treatments.
      Gender Aspects in Skin Diseases

      research Gender aspects in skin diseases

      48 citations , April 2010 in “Journal of the European Academy of Dermatology and Venereology”
      This article reviews gender differences in skin disorders, highlighting variations in disease prevalence and type between sexes, but reports no new findings, emphasizing potential implications for prevention and treatment strategies.
      Alterations of Gut Microbiota Composition in Post-Finasteride Patients: A Pilot Study

      research Alterations of gut microbiota composition in post-finasteride patients: a pilot study

      17 citations , September 2020 in “Journal of Endocrinological Investigation”
      This study found that the gut microbiota composition in patients with post-finasteride syndrome differs significantly from healthy controls, with reduced diversity and specific microbial changes, suggesting a potential diagnostic marker and therapeutic target.
      Transgender Competent Provider

      research Transgender Competent Provider

      16 citations , January 2019 in “Kansas journal of medicine”
      This source outlines what it takes to be a competent provider for transgender individuals, focusing on their health needs, disparities, and coverage, and examines medical biases and hormone treatment guidelines, alongside treatment options for different age groups, concluding with evolving trends in medical education.
      Pregnancy and the Skin

      research Pregnancy and the Skin

      36 citations , April 1990 in “Dermatologic Clinics”
      This review discusses skin changes and dermatoses during pregnancy and reports no clinical findings, emphasizing a need for better understanding of their causes.