research Controlled Delivery of T-box21 Small Interfering RNA Ameliorates Autoimmune Alopecia in a C3H/HeJ Mouse Model
Controlled delivery of specific RNA and IL-4 restored hair growth in mice with autoimmune alopecia.
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research Association Between Genetically Predicted Leukocyte Telomere Length and Non-Scarring Alopecia: A Two-Sample Mendelian Randomization Study
Shorter telomeres in white blood cells may increase the risk of a common type of hair loss.
research Molecular Principles of Hair Follicle Induction and Morphogenesis
Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.
research Expression of mRNA for Androgen Receptor, 5α-Reductase, and 17β-Hydroxysteroid Dehydrogenase in Human Dermal Papilla Cells
Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.
research Disturbed Epidermal Structure in Mice with Temporally Controlled Fatp4 Deficiency
Fatp4 is crucial for healthy skin development and function.
research A Randomized, Double-Blind, Placebo-Controlled, Half-Head Study to Evaluate the Effects of Platelet-Rich Plasma on Androgenetic Alopecia
PRP injections did not significantly improve hair growth in men with androgenetic alopecia.
research Causal Effects of Genetically Determined Metabolites on Androgenetic Alopecia: A Two-Sample Mendelian Randomization Analysis
Certain metabolites can either protect against or increase the risk of hair loss.
research Expression of Foxi3 Is Regulated by Ectodysplasin in Skin Appendage Placodes
Foxi3 expression in developing teeth and hair is controlled by the ectodysplasin pathway.
research Superiority of Dutasteride Over Finasteride in Hair Regrowth and Reversal of Miniaturization in Men With Androgenetic Alopecia: A Randomized Controlled Open-Label, Evaluator-Blinded Study
Dutasteride is more effective than finasteride at increasing hair count and reversing hair thinning in men with hair loss, but both have similar side effects.
research Growth Factor Cocktail Including Fibroblast Growth Factor 9 in the Treatment of Androgenetic Alopecia in Men and Women: A Randomized Controlled Trial
Cellcurin therapy with microneedling increases hair density and thickness in treating hair loss in men and women.
research Efficacy of Low-Level Laser Therapy in Androgenetic Alopecia – A Randomized Controlled Trial
Low-level laser therapy is safe but not significantly better than minoxidil alone for hair growth.
research Evidence That the Satin Hair Mutant Gene Foxq1 Is Among Multiple and Functionally Diverse Regulatory Targets for Hoxc13 During Hair Follicle Differentiation
The gene Foxq1, controlled by Hoxc13, is crucial for hair follicle differentiation.
research Faculty Opinions Recommendation of Efficacy and Safety of a Low-Level Laser Device in the Treatment of Male and Female Pattern Hair Loss: A Multicenter, Randomized, Sham Device-Controlled, Double-Blind Study
research Treatment of Androgenetic Alopecia with 5-Aminolevulinic Acid Photodynamic Therapy: A Randomized, Placebo-Controlled, Split-Scalp Study of Efficacy and Safety
Using 5-aminolevulinic acid photodynamic therapy for hair loss didn't increase hair growth but slightly reduced scalp oiliness, and it was safe with mild side effects.
research Effects of Withania Somnifera Root Extract Serum Application on Hair Health in Healthy Adults: A Prospective, Double-Blind, Randomized, Parallel, Placebo-Controlled Study
Ashwagandha serum improves hair health and quality of life in people with hair loss.
research Efficacy and Safety of Topical Finasteride Spray Solution for Male Androgenetic Alopecia: A Phase III, Randomized, Controlled Clinical Trial
Topical finasteride is an effective and safer treatment for male hair loss.
research A Marine Protein-Based Dietary Supplement for Subclinical Hair Thinning/Loss: Results of a Multisite, Double-Blind, Placebo-Controlled Clinical Trial
The supplement helps improve hair growth and reduce hair shedding.
research Androgenic Alopecia: A Counterproductive Outcome of the Anabolic Effect of Androgens
Male pattern baldness is an unintended side effect of the body's use of androgens for muscle growth, especially in those genetically prone to it.
research Light-Emitting Hair Follicles: Studying Skin Regeneration With In Vivo Imaging
Scientists developed tools to observe hair regeneration in real time and assess skin health, using glowing mice and light-controlled genes.
research Stem Cell Heterogeneity and Plasticity in Epithelia
Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
research Female Pattern Hair Loss
FPHL is a common, age-related, genetic hair loss with unclear causes and limited treatment options.
research Cicatricial (Scarring) Alopecias: Comprehensive Review and Management
Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.
research Two-Photon Microscopy for Intracutaneous Imaging of Stem Cell Activity in Mice
Two-photon microscopy effectively tracks live stem cell activity in mouse skin with minimal harm and clear images.
research Understanding Cancer Cells of Origin in Cutaneous Tumors
The document concludes that identifying the specific cells where skin cancers begin is important for creating better prevention, detection, and treatment methods.
research Hair Transplantation in East Asians
Hair transplantation in East Asians needs special techniques to ensure natural results and prevent complications due to their unique hair and scalp characteristics.
research The Pharmacology of Regenerative Medicine
Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.
research Bioactive Molecules for Skin Repair and Regeneration: Progress and Perspectives
Bioactive molecules show promise for improving skin repair and regeneration by overcoming current challenges with further research.
research A Kaleidoscope of Keratin Gene Expression and the Mosaic of Its Regulatory Mechanisms
Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.
research Selections from Current Literature: Androgenetic Alopecia - The Science Behind a New Oral Treatment
New oral treatment, finasteride, effectively and safely treats common hair loss.
research Topical Application of Thymidine Dinucleotide to Newborn Mice Reduces and Delays Development of UV-Induced Melanomas
Putting thymidine dinucleotide on newborn mice's skin can delay and reduce skin cancer.