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The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

New treatments for Alopecia Areata show promise but need to be more effective and affordable.

Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.

After menopause, women lose a lot of skin collagen, but estrogen replacement might improve skin health.

Some treatments, like corticosteroids and sensitizing agents, can help with alopecia areata, but more high-quality research is needed.

Oral finasteride works better than topical minoxidil for hair growth, both are safe.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

Some parents have a mild form of congenital adrenal hyperplasia without symptoms, and they usually don't need treatment.

Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.

Hair problems can be caused by genetics or the environment, and treatment should focus on the cause and reducing hair damage.

Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.

Hair loss requires customized treatments based on its various causes and types.

No treatments fully cure or prevent alopecia areata; some help but have side effects or need more research.

Acne is common in women, often hormone-related, negatively affects quality of life, and requires various treatments.

Certain microRNAs are more common in balding areas and might be involved in male pattern baldness.

New treatments for psoriasis have improved effectiveness and may reduce long-term side effects when combined with standard therapies.

The document concludes that there is a significant lack of reporting on the sex and age of cells in skin research, which could affect clinical trials and treatments.

Methotrexate effectively treated a 2-year-old's generalized pustular psoriasis without side effects.

Platelet-rich plasma (PRP) is a safe and potentially effective way to treat hair loss, especially when combined with minoxidil.

New genetic insights have improved understanding of hair loss, leading to a new test and treatments, but more research is needed on the test and laser comb effectiveness.

Skin problems in older people can indicate hormonal diseases, nutritional deficiencies, or conditions like diabetes, menopause, and HIV.

Intralesional corticosteroids work best for mild alopecia areata, and DPCP works best for moderate to severe cases.

Primary care for PCOS focuses on lifestyle changes, medication based on symptoms, and mental health, with diabetes screening and specialist referral for severe cases.

The document suggests various treatments for PCOS, including medication for menstrual issues, insulin resistance, and excess hair, as well as fertility treatments, while highlighting the need for personalized care and lifestyle changes.

Hair can indicate early signs of metabolic disorders, with issues like protein deficiency stopping hair growth.

Some people have genetic mutations that make them resistant to vitamin D, leading to rickets even with enough vitamin D intake.