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Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

The study found that sweat glands contain different types of stem cells that help with healing and maintaining healthy skin.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Oral antiandrogens effectively treat female hair loss, with better results in higher hair loss grades.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Alopecia areata is a genetic and immune-related hair loss condition that is often associated with other autoimmune diseases and does not typically cause permanent damage to hair follicles.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

New genetic locations explain much of hair color variation in Europeans.

Lichen planus pigmentosus causes dark skin patches and is treated by avoiding triggers and using anti-inflammatory medications.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.

Researchers found 63 genes linked to male-pattern baldness, which could help in understanding its biology and developing new treatments.

Cancer development is like natural selection, involving mutated cells and environmental factors.

Hair loss gene found on chromosome 3q26.

Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.

Genetic differences between young and old Tan sheep explain why their fleece changes from curly to straight as they age.

Keratins are important for skin cell health and their problems can cause diseases.

New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.