October 2014 in “Journal of Minimally Invasive Gynecology” Genetic testing for cancer risk can lead to early and life-saving treatments in people without symptoms.
43 citations
,
December 2006 in “The American journal of pathology” This study found that Edar signaling plays a role in regulating the hair cycle and apoptosis in hair follicle keratinocytes during the catagen phase in mice.
1 citations
,
January 2022 in “Cell Biology International” This study found that altering cyclin-dependent kinase 4 (CDK4) levels in the bulge region of hair follicles affects the balance of stem cell numbers, potentially influencing hair follicle self-renewal and proliferation.
1 citations
,
May 2004 in “Journal der Deutschen Dermatologischen Gesellschaft” This article from the 4th Intercontinental Meeting of Hair Research Societies provides no abstract or new findings.
January 2011 in “International Journal of Trichology” The conference highlighted new diagnostic tools, the role of genetics in hair loss, and emerging treatments.
This study found that genetic ablation of Tslp in an AEC mutant mouse model reduced skin inflammation and improved survival, suggesting potential therapeutic benefits for AEC syndrome patients.
January 2012 in “International Journal of Trichology” Two siblings have a rare genetic condition causing curly, coarse hair.
21 citations
,
April 2019 in “Clinical, cosmetic and investigational dermatology” This article reviews the causes and clinical presentation of pseudofolliculitis barbae, highlighting how genetic susceptibility and hair removal practices contribute to its development, but reports no new research findings.
January 2013 in “Kidney international” This report describes a clinical case of a 38-year-old man diagnosed with Birt-Hogg-Dubé syndrome, confirmed by genetic testing, highlighting the presentation of multiple renal tumors and bilateral lung cysts.
989 citations
,
August 2007 in “The Lancet” This article reviews the clinical features, diagnostic criteria, and possible genetic and environmental influences of polycystic ovary syndrome but provides no new research findings.
12 citations
,
January 2011 in “Current problems in dermatology” This review covers the use of lasers and IPL for hair removal, noting short-term efficacy up to 6 months and variable long-term results with different devices, emphasizing safety considerations and evolving consumer-based treatments.
July 2023 in “International journal of physiology” This article outlines hypertrichosis lanuginosa, emphasizing its rarity, potential congenital or acquired nature, association with malignancy, challenges in diagnosis, limited treatment options, and the need for more research to understand its mechanisms.
February 2020 in “Acta Scientific Women's Health” This narrative review discusses the various symptoms, diagnosis challenges, and treatment options for polycystic ovary syndrome, emphasizing the need for increased awareness and early diagnosis to prevent complications.
37 citations
,
September 2008 in “The American journal of surgical pathology” This study concluded that hair follicle hyperplasia found in pseudolymphomatous folliculitis can also occur in genuine cutaneous lymphomas, potentially as a coincidental result of underlying pathological processes.
23 citations
,
October 2021 in “Cell Stem Cell” This study found that hair shaft miniaturization in aging and genetic hypotrichosis leads to hair follicle stem cell loss through mechanical compression and apoptosis mediated by the Piezo1 channel.
11 citations
,
May 2003 in “Obstetrics and gynecology (New York. 1953. Online)/Obstetrics and gynecology” This review explores the evaluation and treatment of hirsutism, emphasizing a systematic approach to uncovering its causes and recommending combination therapies for effective management, but presents no new results.
7 citations
,
July 2011 in “Survey of Ophthalmology” This guide provides a comprehensive approach to diagnosing periocular hair disorders, which can range from benign conditions to those posing serious health risks.
3 citations
,
December 1982 in “Australasian journal of dermatology” This article reviews approaches to managing hirsutism but does not report new clinical findings.
2 citations
,
March 2016 in “Serbian Journal of Dermatology and Venerology” This report describes a rare case of congenital generalized hypertrichosis terminalis in a six-year-old boy with gingival hyperplasia, a coarse face, congenital hydronephrosis, and a heterozygous deletion on chromosome 17q12.
October 2023 in “IJEM case reports” This case report describes the diagnosis and management of a 15-year-old girl with complete androgen insensitivity syndrome, highlighting the importance of thorough physical exams for early detection and treatment planning.
January 2021 in “Veterinary research forum” In this study of a Holstein calf with severe congenital ichthyosis, researchers found increased plasma parameters and specific skin changes, highlighting the genetic and incurable nature of this disease in livestock.
April 1999 in “Therapeutische Umschau” This review discusses androgenic alopecia and related hair disorders, focusing on their pathogenesis and treatment strategies, and reports no new clinical findings.
195 citations
,
May 2003 in “Obstetrics and gynecology (New York. 1953. Online)/Obstetrics and gynecology” This review discusses the diagnosis and treatment of hirsutism, emphasizing that a systematic evaluation can determine its cause, while combination therapy effectively manages the condition for most patients.
47 citations
,
August 2000 in “Endocrine Reviews” This review discusses idiopathic hirsutism, potential underlying mechanisms, and various therapeutic approaches without providing new clinical results, and emphasizes the need for further research on well-defined patient groups.
November 2019 in “Harper's Textbook of Pediatric Dermatology” This review discusses potential causes of alopecia and hair overgrowth in pediatric patients, detailing diagnostic techniques and treatments, but presents no new research findings.
April 2019 in “Journal of the Endocrine Society” In this case report, significantly elevated testosterone levels were documented in a young female with Type A Insulin Resistance Syndrome, marking a clinical finding beyond what is typically associated with the disorder's known mutations.
January 2014 in “Jaypee Brothers Medical Publishers (P) Ltd. eBooks” Hair loss is mainly due to genes and hormones, and can be treated with minoxidil and finasteride. Excessive hair growth is linked to certain disorders and can be managed with hormonal therapy and laser hair removal.
6 citations
,
July 2013 in “Acta Clinica Belgica” This review discusses idiopathic hirsutism and suggests that combination treatment, including androgen suppression and cosmetic methods, is most effective, but notes that its pathogenesis remains unclear.
September 2023 in “Journal of the American Academy of Dermatology” A rare benign scalp tumor in an infant requires surgical removal.
May 2025 in “Journal of the ASEAN Federation of Endocrine Societies” This case report discusses a patient with VHL-associated paraganglioma, highlighting the importance of genetic testing and monitoring in those with VHL disease, due to high mutation penetrance and associated risks.