research Intragenic Deletion in the Desmoglein 4 Gene Underlies the Skin Phenotype in the Iffa Credo Hairless Rat
A gene deletion causes the "hairless" trait in Iffa Credo rats.
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research Evidence for a Polygenic Contribution to Androgenetic Alopecia
Hair loss risk is influenced by multiple genes.
research Expanding the Clinical and Mutational Spectrum of Recessive AEBP1-Related Classical-Like Ehlers-Danlos Syndrome
The study concludes that mutations in the AEBP1 gene can cause a form of Ehlers-Danlos syndrome and should be considered in diagnosis.
research Normal and Aging Hair Biology and Structure: Aging and Hair
Hair gets thinner, grayer, and changes texture with age due to genetics, environment, and cellular changes, affecting the growth cycle.
research Chemotherapy-Induced Iatrogenic Injury of Skin: New Drugs and New Concepts
New chemotherapy drugs cause skin side effects, but treatments like minocycline and tetracycline can help reduce them.
research Is There a Pathogenetic Link Between Frontal Fibrosing Alopecia, Androgenetic Alopecia, and Fibrosing Alopecia in a Pattern Distribution?
Frontal fibrosing alopecia and androgenetic alopecia may be related, with a possible shared cause.
research Lupus Erythematosus: Considerations About Clinical, Cutaneous, and Therapeutic Aspects
Lupus treatment requires a combination of drugs and therapies, with research needed for new options.
research High Incidence of Severe Hand-Foot Syndrome During Capecitabine-Docetaxel Combination Chemotherapy
About half the patients treated with capecitabine and docetaxel developed severe hand-foot syndrome.
research Keratin 71 Mutations: From Water Dogs to Woolly Hair
A mutation in the KRT71 gene causes a hair disorder by disrupting hair follicle structure and texture.
research Polycystic Ovary Syndrome: Features, Diagnostic Criteria, and Treatments
PCOS is a long-term condition that needs more research for better understanding and treatment.
research Shedding Light on Therapeutics in Alopecia and Their Relevance to COVID-19
Some alopecia treatments might help treat COVID-19, but more research is needed.
research Disorders of Hair
The document concludes that hair analysis is not good for assessing nutrition but can detect long-term heavy metal exposure.
research Two Birds That Exclude Each Other: The Renbök Phenomenon
Oral tofacitinib can treat both psoriasis and alopecia universalis by normalizing inflammatory pathways.
research Microstructure of Defective Mink Guard Hair
Defective mink guard hairs have split tips and missing cuticle cells, causing a metallic sheen.
research Inheritance-Specific Dysregulation of Th1 and Th17-Associated Cytokines in Alopecia Areata
Certain immune-related proteins are higher in people with alopecia and their healthy relatives, hinting at a genetic link.
research Perturbations in Fatty Acid Metabolism and Collagen Production Infer Pathogenicity of a Novel MBTPS2 Variant in Osteogenesis Imperfecta
A new MBTPS2 gene variant disrupts fat metabolism and collagen production, causing Osteogenesis imperfecta.
research Downstream Molecular Responses to Volatile Signaling in Roots
Plant roots respond to fungus smells by possibly using certain proteins and a plant hormone to change root growth, but more research is needed.
research Discoid Lupus Erythematosus: Comprehensive Overview and Management
Discoid Lupus Erythematosus often causes scarring hair loss, is influenced by genetics and environment, and requires early treatment to prevent worsening.
research Non-Coding Double-Stranded RNA Induces Retinoic Acid Synthesis and Retinoid Signaling to Control Regeneration
Double-stranded RNA helps regenerate hair follicles by increasing retinoic acid production and signaling.
research An Automated Approach Towards Digital Photo-Trichogram for Hair Fall Diagnosis
Researchers developed a computer system to automatically diagnose hair loss by analyzing scalp images.
research Acknowledging the Clinical Heterogeneity of Lupus Erythematosus
Lupus is a complex disease that requires personalized treatment because it varies greatly between individuals.
research Cancer Risk in Polycystic Ovary Syndrome Patients: Common Treatments and Future Perspectives
PCOS may increase the risk of certain cancers.
research An Unusual Cause of Primary Amenorrhea
The 18-year-old girl likely has a condition called müllerian agenesis, which caused her to not have a uterus and experience no menstrual periods.
research Phenotypic Plasticity: Driver of Cancer Initiation, Progression, and Therapy Resistance
Understanding phenotypic plasticity is crucial for developing effective cancer therapies.
research Severe Cutaneous Adverse Reactions to Drugs
Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.
research A Molecular Wound Response Program Associated With Regeneration Initiation in Planarians
Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.
research The Evaluation and Management of Hirsutism
Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.
research Lupus Erythematosus: Systemic and Cutaneous Manifestations
Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.
research Structure of Human Type II 5 Alpha-Reductase Gene
The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.
research Epithelial Skin Biology: Stem Cells and Epidermal Homeostasis
The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.