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The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Researchers found a new gene area linked to male-pattern baldness, which, along with another gene, significantly increases the risk of hair loss in men.

New treatments for Alopecia Areata show promise but need to be more effective and affordable.

Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.

Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.

Genetic differences between young and old Tan sheep explain why their fleece changes from curly to straight as they age.

Keratins are important for skin cell health and their problems can cause diseases.

New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.

The document explains different types of hair loss, their causes, and treatments, and suggests future research areas.

Effective management of children's hair loss involves accurate diagnosis, various treatments, and supportive care.

There's no significant link between the D19S884 marker at the insulin receptor gene and polycystic ovary syndrome.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

Mice are useful for researching human hair loss and testing treatments, despite some differences between species.

Female pattern hair loss involves hormonal factors, genetics, and may be linked to low ferritin levels.

The conclusion is that formalizing how past decisions influence current health technology assessments could improve the credibility and defense of coverage decisions.

Madarosis is the loss of eyelashes and eyebrows due to various health issues and requires thorough examination to diagnose and treat the underlying cause.

Gonadal hormones significantly affect the severity of alopecia areata in mice.

With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.

Certain genetic variations in the FST gene are linked to better wool quality in Chinese Merino sheep.

Using 17-hydroxyprogesterone levels to diagnose nonclassic congenital adrenal hyperplasia can result in many incorrect diagnoses.

PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.

Methotrexate effectively treated a 2-year-old's generalized pustular psoriasis without side effects.

The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Obesity changes androgen levels in women with PCOS, leading to higher testosterone relative to androstenedione.

Hair can indicate early signs of metabolic disorders, with issues like protein deficiency stopping hair growth.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Finasteride reduces prostate cancer risk but may increase high-grade cancer chances.

Scientists found genes linked to hair length in Brangus cattle that could help breed heat-tolerant cattle.

Mutation in hairless gene may increase hair loss risk.