research Neurotrophin-4 Modulates the Mechanotransducer Cav3.2 T-Type Calcium Current in Mice Down-Hair Neurons
Neurotrophin-4 increases calcium current in specific mouse neurons through the PI3K pathway.
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research Molecular Basis for Hair Loss in Mice Carrying a Novel Nonsense Mutation (Hr^rh-R) in the Hairless Gene (Hr)
A new mutation in the hairless gene causes hair loss and skin wrinkling in mice.
research Heterogeneity of Neural Crest-Derived Melanocytes
Melanocytes are diverse cells important for pigmentation and skin health, influenced by genetics and environment.
research Keratin Function and Regulation in Tissue Homeostasis and Pathogenesis
Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.
research Hyperadrenocorticism in Ferrets
Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.
research Impact of Testosterone on Hair and Skin
Testosterone can cause acne and male-pattern baldness, affects hair growth in men and women, and makes male skin more sensitive.
research Pregnancy in Postpartum Estrus Induces Inflammatory Milk Production and Catagen-Specific Pup Skin Inflammation in Interleukin-10 Deficient Mice
Pregnancy right after giving birth in mice lacking IL-10 causes milk that leads to liver issues and hair loss in their babies.
research Comprehensive Overview of Rheumatology Studies: Ottawa, Ontario, Canada, February 13–16, 2013
The document concludes that various findings in rheumatology offer insights into disease severity, treatment responses, and potential risks in medication, with some limitations due to unspecified participant numbers.
research Aberrant Inflammasome Activation as a Driving Force of Human Autoimmune Skin Disease
Faulty inflammasome activation may lead to autoimmune skin diseases and could be a target for new treatments.
research Managing Menopause Chapter 8: Sexuality and Menopause
Menopause often leads to lower sexual desire and discomfort during sex, but treatment should be personalized and only if it bothers the woman.
research Hyperandrogenism in Women: Polycystic Ovary Syndrome
The document concludes that more research is needed to create suitable diagnostic criteria and understand PCOS in Korean women, and genetics may allow for personalized treatment.
research The Genetically Programmed Hair Growth Cycle And Alopecia: What Is There To Know?
The document concludes that hair loss is complex, affects many people, has limited treatments, and requires more research on its causes and psychological impact.
research Vitiligo: A White Patch That Affects the Soul
Vitiligo causes white skin patches and can lead to psychological stress.
research Adult Patients with Aphallia: Were They Fertile?
The document does not determine if adults with aphallia are fertile.
research Drug Permeation Through Hair Follicles: Importance and Potential
Hair follicles are important for drug delivery through the skin, but better methods are needed to understand and improve this process.
research The Relationship Between Keratin 18 and Epithelial-Derived Tumors: As a Diagnostic Marker, Prognostic Marker, and Its Role in Tumorigenesis
Keratin 18 helps diagnose and predict cancer progression and affects cancer growth and spread.
research A Brief Study on Alopecia Areata
Alopecia areata causes hair loss with varied treatment responses and frequent relapses.
research Plant Elicitor Peptides Regulate Root Hair Development in Arabidopsis
Peps help Arabidopsis plants grow more root hairs by affecting specific genes and calcium signaling.
research The Rho GTPase Exchange Factor Vav2 Promotes Extensive Age-Dependent Rewiring of the Hair Follicle Stem Cell Transcriptome
Vav2 changes how hair follicle stem cells' genes work as they age, which might improve regeneration but also raise cancer risk.
research KRT17 Promotes Endometrial Cancer Cell Migration and Angiogenesis by Regulating HIF-1α/VEGF Pathway
KRT17 may be a new target for endometrial cancer treatment because it helps cancer cells move and form new blood vessels.
research Pattern of Skin Disorders Across Age Groups
Skin infections and eczema were most common in all ages, acne in teens and young adults, and nutritional skin problems and infestations in children.
research Conditional Ablation of JAK-STAT5 Signaling Induces Anagen Hair Growth
Blocking JAK-STAT5 signaling in mice leads to hair growth.
research Androgen Biosynthesis and Gene Defects
Gene mutations can cause problems in male genital development.
research Male Pattern Hair Loss: The Selfless Gene
Male pattern hair loss may have evolved to promote younger fathers for offspring health and survival, encouraging monogamy and paternal nurturing.
research Physiologic Skin Changes Associated With Pregnancy
Pregnancy often causes skin changes like darkening, stretch marks, and hair growth, which may improve after childbirth.
research Morpho-Regulation in Diverse Chicken Feather Formation: Integrating Branching Modules and Sex Hormone-Dependent Morpho-Regulatory Modules
Sex hormones, especially estradiol, can change chicken feather shapes and colors.
research Appearance and Internal Aging
Looking older on the outside might be linked to aging faster on the inside and can be affected by lifestyle choices and health risks.
research Familial Aggregation of Phenotypic Expression of Premature Hair Hypopigmentation in the Craniofacial Region
Premature hair graying in the face may be influenced by genetics and environment.
research Root Hair Defective Six-Like 4 (RSL4) Promotes Root Hair Elongation by Transcriptionally Regulating the Expression of Genes Required for Cell Growth
The protein RSL4 is crucial for making root hairs longer by controlling genes related to cell growth.
research Body Site Heterogeneity and Microbial Diversity Is Lost in Individuals with Hidradenitis Suppurativa
People with Hidradenitis Suppurativa have less diverse skin bacteria and different bacterial metabolism than healthy individuals.