August 2026 in “Journal of Genome Biotechnology and Genetics” This review found that while forensic DNA phenotyping and health applications for pigmentation genetics show potential, factors like phenotype definition and population diversity present challenges to accurate genotype-to-appearance predictions.
6 citations
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May 2016 in “Experimental Dermatology” This study by Flores and colleagues found that the type of tumor that develops in a specific subset of epidermal stem cells is influenced by which tumor suppressor gene is deleted.
March 2025 in “Human Genetics and Genomics Advances” This study found that genetic predictions of male pattern baldness from European populations do not generalize well to African populations, highlighting significant differences in genetic architecture between them.
January 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that genetic predictions of male pattern baldness derived from European data do not accurately predict baldness in African populations, highlighting significant continental differences in genetic architecture and evolutionary history.
1 citations
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January 2025 in “JEADV Clinical Practice” This study reported that the AAPPO tool effectively distinguishes between patients with alopecia areata based on scalp hair loss severity, whereas the EQ‐5D‐5L may underestimate the specific disease burden, particularly in psychological and social aspects.
1 citations
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April 2024 in “Science Advances” In this study, researchers found that the female plumage color variations in the common cuckoo are linked to the female-restricted genome and suggest this pattern is maintained by balancing selection, sharing ancestry with the oriental cuckoo.
May 2023 in “Journal of complementary medicine & alternative healthcare” The authors concluded that Ayurveda's concepts of eight undesired body types, such as hereditary obesity and albinism, align with modern genetic understanding, suggesting these traits have genetic predispositions as originally mentioned in ancient Indian medical texts.
2 citations
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December 2024 In this study, the researchers observed that the evolution of Curtobacterium flaccumfaciens pv. flaccumfaciens, which causes tan spot in Australian mungbeans, is driven by clonal expansion from existing genetic variations, emphasizing the need for informed breeding strategies to manage resistance against this pathogen.
October 2024 in “Journal of the Endocrine Society” This study examined uncharacterized CYP21A2 gene variants related to non-classic congenital adrenal hyperplasia and found that several mutations reduce enzyme activity, which may help improve diagnostic and treatment strategies.
October 2024 in “Journal of the Endocrine Society” This study found that certain CYP21A2 mutations significantly reduce enzyme activity, contributing to non-classic congenital adrenal hyperplasia phenotypes, which may aid in enhancing diagnosis and treatment strategies.
37 citations
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November 2017 in “Medical Sciences” This study suggests that melanoma tumor cells exhibit intrinsic plasticity, challenging the applicability of the cancer stem cell model to this malignancy.
27 citations
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April 2020 in “Molecular Biology and Evolution” This study found that ancient and modern Chinese goats share close genetic ties, originating from the Fertile Crescent, with genetic divergence influenced by China's climatic divisions.
16 citations
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November 2022 in “eLife” This study found that specific genetic changes in both coding and noncoding regions may have independently driven the evolution of hairlessness in various mammalian species through accelerated evolution.
9 citations
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July 2011 in “Scientific Reports” This study suggests that human evolution involved accelerated changes in the HR gene, affecting its role in mediating postnatal hair cycling.
This study suggests that specific genetic changes, including mutations in protein-coding genes and noncoding regions, have contributed to the evolution of hairlessness in multiple mammalian species.
38 citations
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October 2006 in “Fertility and Sterility” The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.
152 citations
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January 2004 in “Current anthropology” Humans lost body hair relatively recently in evolution.
48 citations
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May 2015 in “PLOS ONE” This study found that a genetic test using 5 to 20 SNPs can predict male pattern baldness with variable accuracy in European men, especially those aged 50 and older.
3 citations
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May 2018 in “InTech eBooks” This review discusses the evaluation of animal models for hair research and regeneration, highlighting their importance and limitations, and calls for improved approaches to advance understanding of human hair diseases.
This study identified genetic regions evolving at different rates in hairless mammals, suggesting that specific genomic changes may contribute to the evolution of hairlessness across various species.
5 citations
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January 2015 in “Current problems in dermatology” The document provides a practical guide for diagnosing and treating various types of hair loss.
4 citations
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June 2019 in “Journal of Cosmetic Dermatology” In this study, serum omentin-1 levels were significantly higher in females with idiopathic hirsutism compared to those with PCOS and healthy controls.
1 citations
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August 2021 in “Medical Science Monitor” This study found no significant association between genetic loci linked to male androgenetic alopecia and female-pattern hair loss in a Chinese Han population, suggesting they are etiologically separate disorders.
October 2024 in “Skin Appendage Disorders” This study found that lichen planopilaris is associated with several environmental factors, such as stress and hair dye use, as well as thyroid disorders and genetic components.
May 2023 in “Advances in medicine” In this study, Alopecia Areata patients were generally knowledgeable about their condition, believed it was due to genetic or health factors, and experienced significant anxiety and depression affecting their quality of life.
47 citations
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August 2014 in “The Journal of Clinical Endocrinology and Metabolism” This study suggests that variations in PCOS phenotypes observed across different ethnic groups may be due to a genetic gradient resulting from historical human migrations and genetic drift.
4 citations
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January 2020 in “Hair Therapy & Transplantation” This study reviewed the relationship between nutrients and hair loss, emphasizing that individual nutritional deficiencies require specific attention for effective non-pathological treatment, rather than relying on generic dietary supplements often based on tradition or commercial reasons.
10 citations
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May 2023 in “Journal of Investigative Dermatology” In this study, 21.1% of participants had actinic keratoses, with higher prevalence in men, and certain genetic and photoaging factors were positively associated with AK, though smoking was linked to reduced risk.
19 citations
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August 1999 in “European journal of endocrinology” This study concluded that neither basal nor ACTH-stimulated 17-OHP concentrations effectively indicate carrier status for 21-hydroxylase deficiency among Slovenian hyperandrogenic women, recommending molecular analysis of the CYP21 gene for reliable screening.
1 citations
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December 2025 in “World Journal of Biology Pharmacy and Health Sciences” This review highlights that pediatric hirsutism, often linked to endocrine, metabolic, genetic, or neoplastic disorders, requires comprehensive evaluation to prevent long-term health issues, integrating advancements in androgen biosynthesis understanding and diagnostic and management strategies.