Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This chapter discusses the skin stem cell niche as a complex ecosystem and highlights the diverse components and interactions that influence stem cell function, but it reports no new experimental results.

This study found that humans have a significantly slower wound-healing rate compared to non-human primates and other animals, suggesting that slow wound healing is a characteristic unique to humans within the primate order and potentially indicating evolutionary adaptations.

This study identifies novel genetic variants in the NOTCH3 and HTRA1 genes associated with CADASIL and CARASIL, highlighting their potential in supporting clinical diagnosis and informing treatment strategies.

In this study, researchers found that the female plumage color variations in the common cuckoo are linked to the female-restricted genome and suggest this pattern is maintained by balancing selection, sharing ancestry with the oriental cuckoo.

This article discusses the teratogenic risks of skin condition treatments for individuals with DSD and notes that testosterone replacement, often used in this population, may cause acne.

This study observed that numerical chromosomal aberrations were more common in men with severe male factor infertility and azoospermia compared to those with other sperm quality issues, while chromosomal translocations were significantly associated with oligoasthenozoospermia, highlighting important genetic counseling considerations.

This scoping review suggests that physiological differences in skin structure may affect how individuals with different skin tones respond to pressure ulcer development, emphasizing the need for targeted prevention strategies.

This study analyzed changes in the microbiota during antler velvet regeneration in sika deer and found significant differences in microbial community composition between 15 and 30 days post-pedicle casting, highlighting the potential roles of specific bacteria in wound healing and tissue regeneration.

This study found that higher expression of the Hoxc13 gene in specific areas of hair follicles is associated with longer wool length in Gansu alpine fine-wool sheep.

This study found that there was no significant difference between patients' and physicians' assessments of androgenetic alopecia severity, despite variability in individual cases.

This study reviews the genetic mechanisms behind cat coat patterns, revealing that specific loci determine tabby variations and suggesting these patterns could unravel broader developmental and evolutionary biology insights.

Infected shallots have more diverse metabolites, with certain compounds indicating resistance to Fusarium disease.

This review discusses managing prostate cancer in patients with high-risk germline mutations and highlights the need for more research and consensus guidelines, reporting no new clinical results.

In this study, researchers identified genes IRF2BP2 and EGFR as key to understanding double-coated fleece formation in Hetian sheep, offering insights that may advance machine learning-driven multi-omics selection models in sheep breeding.

This study used transcriptome analysis to explore the genetic mechanisms behind the development and seasonal variation of nuptial pads in R. chensinensis, identifying key genes and processes that suggest the pads' development involves complex regulatory pathways, particularly those related to cell cycle and hormone synthesis.

This study highlights the genetic complexities in alopecia areata, emphasizing the role of microRNAs and their association with other immune-related diseases, which could inform targeted treatment strategies.

In this study using human cell cultures, type 1 5α-reductase was found to vary in both protein heterogeneity and expression levels across different types of skin cells.

This study systematically reviewed clinical findings in trichothiodystrophy patients and suggested a new clinico-genetic classification to help better understand the ichthyotic phenotype and its management.

This study found that extreme morning and evening chronotypes exhibited significant differences in the timing of circadian clock gene expression in hair follicle cells.

This review discusses sex and gender differences in COVID-19 presentation, treatment, and outcomes, and reports no new clinical findings.

This study analyzed RNA-seq data from various animal breeds and suggested that similar molecular mechanisms may underlie wool fineness in different sheep breeds. Researchers identified 32 candidate genes related to hair follicle regulation, providing insights for molecular breeding and evolutionary studies.

This study found that higher levels of AR expression are linked to a decreased risk of severe COVID-19 in females, and identified ACE2, MX1, and TMPRSS2 as important molecular markers for COVID-19 management.

This study found that C57BL/6 mice and Sprague–Dawley rats show distinct distributions of eccrine sweat glands and hair follicles in their volar skin, suggesting these models should be selected according to research focus on skin appendages.

In this study, researchers assessed the genetic diversity of 101 Ginkgo biloba individuals using EST-SSR markers and concluded that there is a high level of genetic diversity in Ginkgo populations, facilitating the construction of a core germplasm collection for breeding purposes.

This study used TMT-based quantitative proteomics to analyze the development of secondary hair follicles in fetal sheep, revealing increased follicle density and key proteins involved, such as COL1A1 and THBS4, indicating their potential role in wool quality traits.

Copper may protect against alopecia areata, while certain inflammatory markers increase risk.

This study examined genetic adaptations in Tibetan sheep through whole-genome resequencing, identifying key genes related to hypoxia tolerance, wool color, and body size. These findings provide a foundation for future molecular breeding strategies to enhance wool quality and adaptive traits in these high-altitude environments.

This review examined the role of organoid technology in modeling genetic diseases, highlighting its promise for understanding disease pathology and developing tailored treatments by integrating genetic insights with advancements in regenerative medicine and biological engineering.