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The research suggests that the global distribution of PCOS is likely due to historical human migration and that genes affecting PCOS may have different impacts on males and females.

Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.

Gene therapy has potential as a future treatment for Hutchinson-Gilford progeria syndrome.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

Men's hair loss is caused by hormones and genes, and can be treated with medication and surgery, while graying is due to aging and has no prevention except dyeing.

Female pattern hair loss involves hormonal factors, genetics, and may be linked to low ferritin levels.

The conclusion is that formalizing how past decisions influence current health technology assessments could improve the credibility and defense of coverage decisions.

Gonadal hormones significantly affect the severity of alopecia areata in mice.

The VEGF +405G allele may increase the risk of PCOS in South Indian women.

Hair loss in black women needs more research, early intervention, and community education.

Using 17-hydroxyprogesterone levels to diagnose nonclassic congenital adrenal hyperplasia can result in many incorrect diagnoses.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.

Different processes create patterns in skin and things like hair and feathers.

Methotrexate effectively treated a 2-year-old's generalized pustular psoriasis without side effects.

Frontal Fibrosing Alopecia's cause is unclear, affects mainly postmenopausal women, and current treatments focus on stopping hair loss rather than regrowth.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.

Over 67 genes linked to ichthyosis help improve diagnosis and treatment.

Skin patterns are formed by simple reaction-diffusion mechanisms.

The conclusion is that proper evaluation and treatment of hair loss in midlife women is important, considering the emotional impact and potential for various treatments.

The cause of alopecia areata is likely a mix of genetics, immune system issues, and environmental factors, with more research needed to understand it fully.

The document concludes that more research is needed to fully understand the causes of PCOS.

New treatments and early diagnosis methods for permanent hair loss due to scar tissue are important for managing its psychological effects.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Obesity changes androgen levels in women with PCOS, leading to higher testosterone relative to androstenedione.

Hair loss in certain young mice is linked to a specific gene and can be caused by lack of iron.

Hairless gene not strongly linked to baldness.