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5-alpha reductase inhibitors may cause sexual side effects, breast complications, and other health risks in men with hair loss.

ECM changes may play a role in hair loss, with differences between males and females.

Disrupting the Tsc2 gene in certain cells leads to thicker skin, larger hair, and changes in hair growth signaling, which can be partly reversed with specific treatment.

Genetic factors play a major role in acne.

Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

A genetic defect in vitamin D receptors causes severe rickets and hair loss in children, but some heal as they age.

After menopause, women lose a lot of skin collagen, but estrogen replacement might improve skin health.

Some hair loss can be treated, especially in women due to nutrition, but some types remain untreatable.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Multiple treatments work best for hair loss.

New methods to improve the healing abilities of mesenchymal stem cells for disease treatment are promising but need more research.

Mice with human skin protein K8 had more skin problems and cancer.

Female pattern hair loss has unclear causes, possibly involving genetics, hormones, and environment, and needs better treatments.

Ectodermal dysplasia causes various symptoms and early treatment is important for eye, dental, and skin issues.

Kids with early graying hair often have low levels of calcium, ferritin, and vitamin D3.

The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.

Stress and emotional factors can worsen skin conditions by affecting the immune system.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Gene regulation could revolutionize hair color by altering pigmentation from within.

Hair can indicate early signs of metabolic disorders, with issues like protein deficiency stopping hair growth.

Birt–Hogg–Dubé Syndrome requires genetic testing for accurate diagnosis due to its similarities with tuberous sclerosis.

Betamethasone can effectively treat alopecia areata.

N-acetyl-L-cysteine (NAC) can prevent DNA damage and protect cells from harm.

People with Mucopolysaccharidoses often have skin problems like thick skin and extra hair, and recognizing these can help diagnose and treat the condition early.

Genetic mutations that disrupt homocysteine breakdown lead to increased damage in mouse hair keratin.

Where a rhesus macaque used to live can affect its chances of getting alopecia later in life, and females are more likely to be affected than males.